MRNA HIV vaccine trial launches in south africa – could this be a game changer?

NCT ID NCT06694753

First seen Jan 05, 2026 · Last updated May 24, 2026 · Updated 24 times

Summary

This early-stage study tests three experimental mRNA vaccines designed to train the immune system to fight HIV. About 96 healthy adults without HIV in South Africa will receive either the vaccine or a placebo. The main goals are to check safety and see if the vaccines trigger strong immune responses that could one day prevent infection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • CAPRISA eThekwini CRS

    RECRUITING

    Durban, KwaZulu-Natal, 4001, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Desmond Tutu Health Foundation Emavundleni CRS

    RECRUITING

    Cape Town, Western Cape, 7750, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Desmond Tutu Health Foundation- Groote Schuur Hospital/J52

    RECRUITING

    Cape Town, Western Cape, 7925, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Isipingo CRS

    RECRUITING

    Isipingo, KwaZulu-Natal, 4110, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Perinatal HIV Research Unit (PHRU)

    RECRUITING

    Soweto, Gauteng, 1862, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Setshaba Research Centre CRS

    RECRUITING

    Soshanguve, Gauteng, 0152, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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