New HIV pill study: could a simpler 2-drug regimen match a standard 3-drug combo?
NCT ID NCT05979311
First seen Jan 04, 2026 · Last updated Apr 26, 2026 · Updated 15 times
Summary
This study tests whether a two-drug HIV pill (dolutegravir/lamivudine) works as well as a three-drug pill (bictegravir/emtricitabine/tenofovir alafenamide) for adults who have never taken HIV medication before. About 473 participants will take one of the two pills daily for up to 96 weeks. The main goal is to see if both treatments keep the virus at very low levels in the blood. This is a disease control study, not a cure, because people with HIV need lifelong treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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GSK Investigational Site
Ciudad Autonoma de Buenos Aire, C1425AWK, Argentina
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GSK Investigational Site
Córdoba, X5000JJS, Argentina
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GSK Investigational Site
Antwerp, 2000, Belgium
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GSK Investigational Site
Brussels, 1000, Belgium
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GSK Investigational Site
Ghent, 9000, Belgium
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GSK Investigational Site
Hvidovre, 2650, Denmark
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GSK Investigational Site
Bordeaux, 33000, France
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GSK Investigational Site
Bordeaux, 33076, France
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GSK Investigational Site
Lyon, 31059, France
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GSK Investigational Site
Montpellier, 34090, France
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GSK Investigational Site
Nice, 06202, France
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GSK Investigational Site
Nîmes, 30029, France
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GSK Investigational Site
Paris, 75012, France
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GSK Investigational Site
Paris, 75013, France
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GSK Investigational Site
Paris, 75018, France
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GSK Investigational Site
Paris, 75970, France
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GSK Investigational Site
Berlin, 10787, Germany
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GSK Investigational Site
Cologne, 50668, Germany
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GSK Investigational Site
Frankfurt, 60590, Germany
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GSK Investigational Site
Hamburg, 20146, Germany
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GSK Investigational Site
München, 80336, Germany
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GSK Investigational Site
Athens, 106 76, Greece
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GSK Investigational Site
Athens, 11 527, Greece
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GSK Investigational Site
Thessaloniki, 54635, Greece
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GSK Investigational Site
Dublin, 7, Ireland
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GSK Investigational Site
Dublin, D09 V2N0, Ireland
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GSK Investigational Site
Haifa, 31096, Israel
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GSK Investigational Site
Ramat Gan, 52621, Israel
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GSK Investigational Site
Rehovot, 76100, Israel
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GSK Investigational Site
Tel Aviv, 64239, Israel
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GSK Investigational Site
Bari, 70124, Italy
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GSK Investigational Site
Bergamo, 24127, Italy
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GSK Investigational Site
Padova, 35128, Italy
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GSK Investigational Site
Pavia, 27100, Italy
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GSK Investigational Site
Sassari, 07100, Italy
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GSK Investigational Site
Aichi, 460-0001, Japan
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GSK Investigational Site
Osaka, 540-0006, Japan
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GSK Investigational Site
Tokyo, 108-8639, Japan
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GSK Investigational Site
Tokyo, 162-8655, Japan
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GSK Investigational Site
Mérida, 97070, Mexico
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GSK Investigational Site
Bydgoszcz, 85-030, Poland
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GSK Investigational Site
Lodz, 91-347, Poland
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GSK Investigational Site
Wroclaw, 50-136, Poland
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GSK Investigational Site
Aveiro, 3814-501, Portugal
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GSK Investigational Site
Porto, 4099-001, Portugal
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GSK Investigational Site
Badalona, 08916, Spain
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GSK Investigational Site
Barcelona, 08036, Spain
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GSK Investigational Site
Elche Alicante, 03203, Spain
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GSK Investigational Site
La Laguna-Tenerife, 35010, Spain
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GSK Investigational Site
Madrid, 28040, Spain
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GSK Investigational Site
Madrid, 28041, Spain
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GSK Investigational Site
Madrid, 28046, Spain
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GSK Investigational Site
Marbella, 29603, Spain
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GSK Investigational Site
Palma de Mallorca, 07120, Spain
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GSK Investigational Site
Palma de Mallorca, 7198, Spain
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GSK Investigational Site
Valencia, 46014, Spain
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GSK Investigational Site
Stockholm, SE-14186, Sweden
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GSK Investigational Site
Basel, 4031, Switzerland
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GSK Investigational Site
Zurich, 8005, Switzerland
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GSK Investigational Site
Glasgow, G12 OYN, United Kingdom
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GSK Investigational Site
London, E9 6SR, United Kingdom
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GSK Investigational Site
London, SE5 8AF, United Kingdom
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GSK Investigational Site
London, W1D 6AQ, United Kingdom
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GSK Investigational Site
London, W2 1NY, United Kingdom
Conditions
Explore the condition pages connected to this study.