HIV breakthrough trial seeks to rescue failing treatments in africa

NCT ID NCT05373758

First seen Mar 30, 2026 · Last updated May 29, 2026 · Updated 3 times

Summary

This study tests different approaches to help people with HIV whose current medication (tenofovir, lamivudine, and dolutegravir, or TLD) is no longer working. It involves 648 adults and teens in Uganda and South Africa. The goal is to find the best strategy to get the virus under control again, measured by a very low viral load after 48 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mbarara City Clinic

    RECRUITING

    Mbarara, Uganda

    Contact

    Contact

  • Mbarara Regional Referral Hospital Immune Suppression Syndrome Clinic

    RECRUITING

    Mbarara, Uganda

    Contact

    Contact

  • RK Khan Hospital Clinic

    RECRUITING

    Durban, South Africa

    Contact

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.