Could a combined therapy boost HIV care in south africa?

NCT ID NCT06152003

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to develop and pilot a program for people with HIV in South Africa who also face depression, trauma, and food insecurity. Researchers will first explore how these problems interact, then create a treatment called CBT-SA that combines therapy, nutrition support, and case management. The pilot will test whether 60 participants find the program acceptable and feasible, with a focus on improving HIV medication adherence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive Behavioral Therapy for Syndemics and Adherence (CBT-SA) combined with nutritional counseling, food parcels, case management, and linkage to care

What this could lead to

If successful, this could point toward a practical treatment package that improves both mental health and HIV medication adherence in underserved communities.

What could go wrong

This is a very early pilot study with only 60 participants, so results may not apply broadly. The intervention is complex and may be difficult to deliver consistently.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression HIV infectious disease post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Cape Town

    Cape Town, Western Cape, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••