Experimental mRNA vaccines against HIV enter human safety trials

NCT ID NCT05217641

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This early-stage study tests three experimental mRNA vaccines designed to train the immune system against HIV. Researchers want to see if the vaccines are safe and whether they trigger the body to make antibodies that can neutralize the virus. The trial involves 108 healthy adults who are not infected with HIV.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alabama CRS [31788]

    Birmingham, Alabama, 35222, United States

  • Bidmc Vcrs [32077]

    Boston, Massachusetts, 02115, United States

  • Brigham and Women's Hospital Vaccine CRS [30007]

    Boston, Massachusetts, 02115, United States

  • Columbia P&S CRS [30329]

    New York, New York, 30329, United States

  • New York Blood Center CRS [31801]

    New York, New York, 10065, United States

  • Penn Prevention CRS [30310]

    Philadelphia, Pennsylvania, 19104, United States

  • Seattle Vaccine and Prevention CRS [30331]

    Seattle, Washington, 98104, United States

  • UCLA Vine Street Clinic CRS [31607]

    Los Angeles, California, 90038, United States

  • University of Pittsburgh CRS [1001]

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Rochester Vaccines to Prevent HIV Infection CRS [31467]

    Rochester, New York, 14642, United States

Conditions

Explore the condition pages connected to this study.