HIV memory mystery: even controlled virus may harm the brain
NCT ID NCT01875588
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 12 times
Summary
This study looks at why some people with HIV who have very low virus levels in their blood still develop thinking and memory problems. Researchers will follow 1,150 participants—including healthy volunteers—for up to 10 years, using brain scans, blood tests, and spinal fluid samples. The goal is to better understand how HIV might affect the brain even when medications keep the virus in check.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand why memory and thinking problems occur in people with well-controlled HIV, potentially pointing toward future treatments.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly improve health. It may take years to gather enough data, and findings might not apply to everyone with HIV.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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