Could a Twice-a-Month shot replace daily HIV meds?

NCT ID NCT07215468

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This study tests whether a combination of two antibodies (TMB-365 and TMB-380) given as an IV infusion every 8 weeks can keep HIV under control in people who are already suppressed on daily oral medication. About 75 adults with HIV will either switch to the antibody infusions or stay on their daily pills for 48 weeks. The goal is to see if the antibody combo works as well as daily pills to maintain viral suppression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CAN Community Health Fort Lauderdale

    RECRUITING

    Fort Lauderdale, Florida, 33316, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CAN Community Health Las Vegas

    RECRUITING

    Las Vegas, Nevada, 89104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CAN Community Health Miami Gardens

    RECRUITING

    Miami Gardens, Florida, 33055, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CAN Community Health Sarasota

    RECRUITING

    Sarasota, Florida, 34237, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Midland Medical

    RECRUITING

    Oakland Park, Florida, 33334, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Midway Immunology and Research Center (MIRC)

    RECRUITING

    Ft. Pierce, Florida, 34982, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orlando Immunology Center

    RECRUITING

    Orlando, Florida, 32803, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Quest Clinical Research

    RECRUITING

    San Francisco, California, 94115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Crofoot Research Center, Inc.

    RECRUITING

    Houston, Texas, 77098, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Rockefeller University

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.