HIV heart shield: drug combo targets weight and cholesterol

NCT ID NCT06317051

First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 16 times

Summary

This study tests two drug combinations in 300 people with HIV who have gained weight or have high cholesterol from their HIV medications. One part compares dapagliflozin (a diabetes drug) to a placebo for weight loss. The other compares a two-statin combo to a single statin for lowering cholesterol. The goal is to reduce heart disease risk without changing HIV treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Austin Health

    Melbourne, Victoria, 3084, Australia

  • CART-CRS

    Chennai, Tamil Nadu, 600113, India

  • Desmond Tutu Health Foundation

    Cape Town, 7925, South Africa

  • HIV-NAT

    Bangkok, Thailand

  • Hospital Ramos Mejía

    Buenos Aires, Argentina

  • Infectious Diseases Institute, Makerere University

    Kampala, Uganda

  • Institute of Human Virology, Nigeria

    Abuja, Nigeria

  • St Vincent's Hospital

    Sydney, New South Wales, 2010, Australia

  • Universiti Malaya Medical Centre

    Kuala Lumpur, Malaysia

  • University of Zimbabwe Clinical Research Centre

    Harare, Zimbabwe

Conditions

Explore the condition pages connected to this study.