HIV drug levels in hidden reservoirs: new study maps where virus hides
NCT ID NCT04133012
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 20 men with HIV who were stable on a common drug combination. Researchers took samples of blood, lymph nodes, rectal tissue, fat, and semen to measure how much of the drugs reached these areas. The goal was to understand why HIV can still hide in some tissues even when treatment seems to work. This is a small, completed study that does not test a new treatment but aims to improve knowledge about HIV persistence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dolutegravir, abacavir, lamivudine, tenofovir, emtricitabine
What this could lead to
If successful, this could help doctors understand why HIV sometimes persists even when drugs are working, potentially leading to better treatment strategies.
What could go wrong
This is a small, observational study with only 20 participants. It does not test a new treatment, so it won't directly improve patient care. Results may not apply to all HIV patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HIV-1-INFECTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Antoine-Beclere Hospital
Clamart, France
-
Bicetre Hospital
Le Kremlin-Bicêtre, France
-
Bichat Hospital
Paris, France
-
Hotel Dieu Hospital
Paris, France
-
Necker Hospital
Paris, France
-
Pitie Salpetriere Hospital
Paris, France
-
Saint Antoine Hospital
Paris, 75012, France
-
Tourcoing Hospital
Tourcoing, 59208, France