HIV drug levels in hidden reservoirs: new study maps where virus hides
NCT ID NCT04133012
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 20 men with HIV who were stable on a common drug combination. Researchers took samples of blood, lymph nodes, rectal tissue, fat, and semen to measure how much of the drugs reached these areas. The goal was to understand why HIV can still hide in some tissues even when treatment seems to work. This is a small, completed study that does not test a new treatment but aims to improve knowledge about HIV persistence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dolutegravir, abacavir, lamivudine, tenofovir, emtricitabine
- What this could lead to
- If successful, this could help doctors understand why HIV sometimes persists even when drugs are working, potentially leading to better treatment strategies.
- What could go wrong
- This is a small, observational study with only 20 participants. It does not test a new treatment, so it won't directly improve patient care. Results may not apply to all HIV patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Antoine-Beclere Hospital
Clamart, France
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Bicetre Hospital
Le Kremlin-Bicêtre, France
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Bichat Hospital
Paris, France
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Hotel Dieu Hospital
Paris, France
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Necker Hospital
Paris, France
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Pitie Salpetriere Hospital
Paris, France
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Saint Antoine Hospital
Paris, 75012, France
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Tourcoing Hospital
Tourcoing, 59208, France
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