New HIV combo therapy shows promise in small safety trial

NCT ID NCT05281510

First seen Jan 18, 2026 · Last updated May 12, 2026 · Updated 17 times

Summary

This study tested whether a combination of two lab-made HIV antibodies (VRC07-523LS and CAP256V2LS) followed by an immune-boosting drug (vesatolimod) is safe for women with HIV who are already on standard antiretroviral therapy (ART). The 20 participants were all women from a specific HIV research cohort. The main goal was to check for side effects, not to cure HIV, so participants stayed on their regular HIV medications throughout.

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Contacts and locations

Locations

  • FRESH Clinical Research Site: Females Rising through Education, Support and Health

    Umlazi, 4066, South Africa

Conditions

Explore the condition pages connected to this study.