HIV patients may ditch daily pills for Twice-Yearly antibody shots

NCT ID NCT05275998

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 26 times

Summary

This study tested a combination of two lab-made antibodies (TMB-365 and TMB-380) in 51 adults with HIV whose virus was already well-controlled by daily oral medication. The goal was to see if these antibodies, given as intravenous infusions every 8 weeks, could safely keep the virus suppressed without needing daily pills. The study focused on safety, drug levels in the body, and whether the virus stayed undetectable for 24 weeks after stopping oral therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CAN Community Health

    Fort Lauderdale, Florida, 33316, United States

  • Crofoot Research Center, Inc.

    Houston, Texas, 77098, United States

  • Midway Immunology and Research Center

    Ft. Pierce, Florida, 34892, United States

  • North Texas Infectious Disease Consultants

    Dallas, Texas, 75246, United States

  • Orlando Immunology Center

    Orlando, Florida, 32803, United States

  • Quest Clinical Research

    San Francisco, California, 94115, United States

Conditions

Explore the condition pages connected to this study.