New HIV pill for kids shows promise in ongoing study

NCT ID NCT02881320

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study is testing a new once-daily pill (Bictegravir/Emtricitabine/Tenofovir Alafenamide) for HIV-1 in adolescents and children. The goal is to see how the drug works in the body, confirm the right dose, and check its safety. About 177 participants aged 2 to 17 who already have their HIV under control will take the pill for up to 48 weeks. This is not a cure, but aims to keep the virus suppressed with a simpler treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine Children's Foundation - Uganda

    Kampala, Uganda

  • Be Part Ypluntu Centre

    Cape Town, 7646, South Africa

  • Bellevue Hospital

    New York, New York, 10016, United States

  • Children's National Health System

    Washington D.C., District of Columbia, 20010, United States

  • Department of Paediatrics and Child Health

    Bloemfontein, 9301, South Africa

  • Dr. J Fourie Medical Centre

    Dundee, 3000, South Africa

  • Duke Children's Health Center, Pediatric Infectious Diseases

    Durham, North Carolina, 27710, United States

  • Empilweni Service and Research Unit (ESRU)

    Johannesburg, 2112, South Africa

  • Enhancing Care Foundation, Durban International Clinical Research Site

    Durban, 4302, South Africa

  • FAMCRU, Ward J8

    CapeTown, 7505, South Africa

  • Faculty of Medicine Siriraj Hospital, Mahidol University

    Bangkok, 10700, Thailand

  • Faculty of Medicine, Khon Kaen University

    Khon Kaen, 40002, Thailand

  • Grady Health System Ponce Center Family and Youth Clinic

    Atlanta, Georgia, 30322, United States

  • Joint Clinical Research Centre

    Kampala, 10005, Uganda

  • Makerere University, Johns Hopkins (MU-JHU) Research Collaboration

    Kampala, 0000, Uganda

  • Midway Immunology and Research Center

    Ft. Pierce, Florida, 34982, United States

  • Perinatal HIV Research Unit

    Soweto, 2013, South Africa

  • St. Christopher's Hospital for Children/Section of Immunology

    Philadelphia, Pennsylvania, 19134, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • The HIV Netherlands Australia Thailand Research Collaboration

    Bangkok, 10330, Thailand

  • USF Clinic at Children's Medical Services (study visits and drug storage)

    Tampa, Florida, 33606, United States

  • University of Florida Health

    Gainesville, Florida, 32209, United States

  • VX Pharma(Pty) Ltd

    Pretoria, 0087, South Africa

  • Wayne Pediatric Clinic

    Detroit, Michigan, 48201, United States

  • Wits RHI Shandukani Research Centre, Wits Reproductive Health & HIV Institute

    Johannesburg, 2038, South Africa

Conditions

Explore the condition pages connected to this study.