Could a One-Time high dose beat daily shots for histoplasmosis?

NCT ID NCT07261150

First seen Jan 05, 2026 · Last updated May 20, 2026 · Updated 15 times

Summary

This study tests if a single high dose of an IV antifungal works as well as the standard daily dose for treating moderate to severe histoplasmosis, a serious lung infection. It also compares two oral medications and shorter treatment duration (6 vs 12 months) for people with HIV. The trial aims to find safer, more effective, and simpler treatment options for 664 hospitalized adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Universidade Federal de Ciências da Saúde de Porto Alegre

    Porto Alegre, Brazil

    Contact Email: •••••@•••••

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.