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Heated chemotherapy shows promise for advanced pancreatic cancer

NCT ID NCT04858009

Recruiting now Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests a treatment called HIPEC, where heated chemotherapy drugs are placed directly into the abdomen during surgery. It is for people with pancreatic cancer that has spread to the lining of the abdomen. The study will enroll 40 participants to see if this approach can improve survival and control the cancer safely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
heated chemotherapy (cisplatin and nab-paclitaxel) delivered directly into the abdomen
What this could lead to
If it works, this could offer a new treatment option to control pancreatic cancer that has spread to the abdomen, potentially extending survival.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. Heated chemotherapy carries risks like infection, organ damage, and side effects from the drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma malignant pancreatic neoplasm metastatic malignant neoplasm pancreatic adenocarcinoma pancreatic neoplasm peritoneum cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC MALIGNANT NEOPLASM IN THE PERITONEUM METASTATIC PANCREATIC CARCINOMA STAGE IV PANCREATIC CANCER AJCC V8

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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