Heated chemo during surgery could extend lives in ovarian cancer
NCT ID NCT05827523
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether adding heated chemotherapy (HIPEC) directly into the abdomen during surgery can help people with advanced ovarian cancer live longer. About 520 participants who have already had some chemo will be randomly assigned to get surgery with or without HIPEC. The main goal is to see if HIPEC improves overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cisplatin (heated chemotherapy given directly into the abdomen during surgery)
What this could lead to
If this works, it could become a standard addition to surgery for advanced ovarian cancer, potentially helping people live longer.
What could go wrong
This is a large Phase 3 trial, but heated chemotherapy has risks like infection or organ damage. It may not improve survival enough to outweigh those risks.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ajou University Hospital
RECRUITINGSuwon, Gyeonggi-do, South Korea
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Asan Medical Center
NOT_YET_RECRUITINGSeoul, South Korea
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Chungnam National University Hospital
NOT_YET_RECRUITINGSejong, Chungcheongnam-do, South Korea
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Chungnam National University Sejong Hospital
NOT_YET_RECRUITINGSejong, Chungcheongnam-do, South Korea
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Ewha Womans University Mokdong Hospital
NOT_YET_RECRUITINGSeoul, South Korea
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Ilsan CHA University Hospital
RECRUITINGGoyang-si, Gyeonggi-do, South Korea
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National Cancer Center
RECRUITINGGoyang-si, Gyeonggi-do, South Korea
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pusan National University Hospital
NOT_YET_RECRUITINGPusan, South Korea
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Pusan National University Yangsan Hospital
NOT_YET_RECRUITINGPusan, South Korea
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Severance Hospital
RECRUITINGSeoul, South Korea