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Could short bursts of exercise help people with MS walk farther?

NCT ID NCT07771868

Symptom relief Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This study tests whether a short, intense cycling workout, known as high-intensity interval training (HIIT), can help people with multiple sclerosis (MS) walk farther and feel better in daily life. The trial includes 30 adults with MS at different disability levels, from mild to severe. Participants will do a 20-minute cycling routine several times a week, and researchers will measure walking distance, fatigue, balance, strength, and quality of life before, right after, and four weeks after the program. The goal is to see if HIIT can be tailored to each person's disability level for better results.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-Intensity Interval Training (HIIT) on a stationary bicycle
What this could lead to
If effective, this could help tailor exercise programs to individual disability levels, potentially improving mobility and quality of life for people with MS.
What could go wrong
This is a small, early-stage trial with 30 participants, so results may not apply broadly. HIIT is intense and may be challenging for those with severe disability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be between the ages of 18 and 65, * Have been diagnosed with MS by a treating physician, * Have an EDSS score between 0 and 6.5, * Not having experienced a relapse within the last 3 months, * Not having severe lower extremity contractures, severe spasticity (≥3 on the Modified Ashworth Scale), or an acute orthopedic problem that would prevent the participant from pedaling on a bicycle ergometer, * Having a Mini Mental State Examination score of ≥24. Exclusion Criteria: * Having a severe cardiovascular, orthopedic, respiratory, or metabolic disease, * Having an additional neurological condition, * Being pregnant or suspecting pregnancy, * Having received a botulinum toxin injection within the last 3 months, * Having a COMPASS-31 total score greater than 13.6

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multipl sclerosi̇S

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hatay Mustafa Kemal Universty

    Hatay, Turkey (Türkiye)

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