Could a 2-Month TB treatment be as good as 4 months?

NCT ID NCT03988933

First seen Apr 18, 2026 · Last updated Apr 30, 2026 · Updated 2 times

Summary

This study tested whether taking a higher dose of the antibiotic rifampin for 2 months is as safe and effective as the standard dose taken for 4 months to treat latent tuberculosis (TB). About 1,368 adults and children aged 10 and older with latent TB took part. The goal was to see if a shorter treatment could work just as well without causing more side effects.

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Contacts and locations

Locations

  • BCCDC TB clinic

    Vancouver, British Columbia, Canada

  • Hai Ba Trung District Health Center, No. 16B

    Hà Nội, Vietnam

  • Hanoi Lung Hospital

    Hà Nội, Vietnam

  • MUHC

    Montreal, Quebec, H4A 3J1, Canada

  • Nam Tu Liem District Health Center, No. 3

    Hà Nội, Vietnam

  • Phoi Viet TB and Respiratory Diseases Clinic.

    Ho Chi Minh City, Vietnam

  • The Governors of the University of Alberta

    Edmonton, Alberta, T6G 2C8, Canada

  • Universitas Padjadjaran, Klinik Penelitian Tuberculosis (TB research clinic)

    Bandung, Indonesia

  • Unviversity of Calgary

    Calgary, Alberta, Canada

Conditions

Explore the condition pages connected to this study.