Virtual reality and robots put to the test in neuromuscular rehab

NCT ID NCT06881979

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers are testing whether rehabilitation that uses virtual reality, robotic devices, and balance platforms works as well as traditional therapy for adults with chronic neuromuscular diseases such as ALS, CIDP, and Charcot-Marie-Tooth disease. The trial enrolls about 60 people who can walk independently or with assistance. Participants are assigned to either the high-tech rehabilitation group or the traditional rehabilitation group, and researchers compare changes in fatigue, balance, mobility, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-tech rehabilitation using virtual reality, robotic devices, and stabilometric platforms
What this could lead to
If high-tech rehab matches traditional therapy, clinics could offer engaging, technology-assisted options for managing fatigue and movement problems in chronic neuromuscular disease.
What could go wrong
The trial is small and tests non-inferiority, so it may not show that high-tech rehab is as good as traditional therapy. Equipment-based training may not suit everyone, and results in these specific diseases may not apply to other conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a confirmed diagnosis of chronic neuromuscular diseases (e.g. ALS, CIDP, CMT) * Patient able to walk independently or with assistance * Patients capable of understanding and adhering to the study protocol. * Patients who have provided informed consent to participate in the study Exclusion Criteria: * Patients with unstable medical conditions (e.g. severe cardiovascular diseases, such as "New York Heart Association" - NYHA=4, respiratory distress not compensated by ventilation) that could interfere, in the clinician's judgment, with their ability to safely participate in the study or to perform the assessments related to the protocol. * Patients currently participating in other clinical trials that could interfere with this study. * Pregnant women.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Amyotrophic lateral sclerosis are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Azienda Ospedaliero-Universitaria di Modena

    NOT_YET_RECRUITING

    Modena, 41126, Italy

  • Fondazione Don Carlo Gnocchi Onlus

    NOT_YET_RECRUITING

    Roma, 00135, Italy

  • IRCCS Azienda Ospedaliera Universitaria San Martino - Genova

    NOT_YET_RECRUITING

    Genova, 16132, Italy

  • Istituti Clinici Scientifici Maugeri

    NOT_YET_RECRUITING

    Montescano, 27040, Italy

  • Istituti Clinici Scientifici Maugeri IRCCS

    NOT_YET_RECRUITING

    Pavia, 27100, Italy

  • Istituti Clinici Scientifici Maugeri IRCCS

    NOT_YET_RECRUITING

    Telese Terme, 82037, Italy

  • Istituti Clinici Scientifici Maugeri IRCCS, Milan Institute

    RECRUITING

    Milan, 20138, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.