Virtual reality and robots put to the test in neuromuscular rehab
NCT ID NCT06881979
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are testing whether rehabilitation that uses virtual reality, robotic devices, and balance platforms works as well as traditional therapy for adults with chronic neuromuscular diseases such as ALS, CIDP, and Charcot-Marie-Tooth disease. The trial enrolls about 60 people who can walk independently or with assistance. Participants are assigned to either the high-tech rehabilitation group or the traditional rehabilitation group, and researchers compare changes in fatigue, balance, mobility, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-tech rehabilitation using virtual reality, robotic devices, and stabilometric platforms
- What this could lead to
- If high-tech rehab matches traditional therapy, clinics could offer engaging, technology-assisted options for managing fatigue and movement problems in chronic neuromuscular disease.
- What could go wrong
- The trial is small and tests non-inferiority, so it may not show that high-tech rehab is as good as traditional therapy. Equipment-based training may not suit everyone, and results in these specific diseases may not apply to other conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with a confirmed diagnosis of chronic neuromuscular diseases (e.g. ALS, CIDP, CMT) * Patient able to walk independently or with assistance * Patients capable of understanding and adhering to the study protocol. * Patients who have provided informed consent to participate in the study Exclusion Criteria: * Patients with unstable medical conditions (e.g. severe cardiovascular diseases, such as "New York Heart Association" - NYHA=4, respiratory distress not compensated by ventilation) that could interfere, in the clinician's judgment, with their ability to safely participate in the study or to perform the assessments related to the protocol. * Patients currently participating in other clinical trials that could interfere with this study. * Pregnant women.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
7 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Azienda Ospedaliero-Universitaria di Modena
NOT_YET_RECRUITINGModena, 41126, Italy
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Fondazione Don Carlo Gnocchi Onlus
NOT_YET_RECRUITINGRoma, 00135, Italy
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IRCCS Azienda Ospedaliera Universitaria San Martino - Genova
NOT_YET_RECRUITINGGenova, 16132, Italy
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Istituti Clinici Scientifici Maugeri
NOT_YET_RECRUITINGMontescano, 27040, Italy
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Istituti Clinici Scientifici Maugeri IRCCS
NOT_YET_RECRUITINGPavia, 27100, Italy
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Istituti Clinici Scientifici Maugeri IRCCS
NOT_YET_RECRUITINGTelese Terme, 82037, Italy
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Istituti Clinici Scientifici Maugeri IRCCS, Milan Institute
RECRUITINGMilan, 20138, Italy
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- Can a NAD-Boosting supplement slow ALS? extension trial tests nicotinamide riboside and pterostilbene
- Breathing support in ALS: what it means for patients and families
- Global registry aims to map the full course of Charcot-Marie-Tooth disease
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- Can hospital codes reliably track home ventilation in ALS?