Extra oxygen may boost exercise in lung disease patients

NCT ID NCT02551068

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether breathing 60% oxygen during exercise helps people with idiopathic pulmonary fibrosis (IPF) who are taking nintedanib. 78 participants exercised on a bike or walked while getting either high oxygen or standard care. The goal was to see if they could exercise longer and feel less breathless after 8 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
60% oxygen
What this could lead to
If it works, this could point toward a simple way to help IPF patients exercise longer and feel less breathless.
What could go wrong
This is a small, completed study with 78 participants. The results may not apply to all IPF patients, and the benefit may be modest.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Laval University

    Québec, Quebec, G1V 0A6, Canada

  • McGill University

    Montreal, Quebec, H3A 0G4, Canada

  • McMaster University

    Hamilton, Ontario, L8S 4L8, Canada

  • Queens University

    Kingston, Ontario, K7L 3N6, Canada

  • St. Paul's Hospital

    Vancouver, British Columbia, V6Z1Y6, Canada

  • UBC Okanagan

    Kelowna, British Columbia, V1V 1V7, Canada

  • University of Alberta

    Edmonton, Alberta, T6G 2R3, Canada

  • University of Calgary

    Calgary, Alberta, T3M1M4, Canada

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