European study seeks clues to mysterious eye bulge in severe myopia

NCT ID NCT06949579

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study looks at 200 highly myopic adults in France, the Netherlands, and Spain to understand why some develop a condition called posterior staphyloma, where the back of the eye bulges outward. Researchers will analyze blood samples and eye images to find genetic and molecular differences between those with and without the condition. The goal is to better understand the causes, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could improve understanding of why some highly myopic people develop posterior staphyloma, potentially guiding future screening or prevention strategies.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to new therapies, and findings might not apply to non-European populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIGH MYOPIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

degenerative myopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIGH MYOPIA

Contacts and locations

Locations

Cochin Hospital
RECRUITING

Paris, 75014, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.