Can short bursts of hard exercise ease bronchiectasis?

NCT ID NCT07805174

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Sep 04, 2026 · Last updated Sep 04, 2026

Summary

This study tests whether high-intensity interval exercise, short bursts of hard effort with rest in between, can help adults with non-cystic fibrosis bronchiectasis. Participants will either do this exercise plus airway clearance techniques, or only the clearance techniques, three days a week for eight weeks. Researchers will measure breathing, walking ability, muscle strength, and quality of life to see if the exercise adds real benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-intensity interval exercise
What this could lead to
If effective, this exercise program could become a standard addition to airway clearance therapy, helping people with bronchiectasis breathe easier, move more, and feel better day to day.
What could go wrong
The trial is small and early, so results may not apply to everyone. High-intensity exercise carries risks like shortness of breath or injury, and it may not improve symptoms more than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 42 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Being over 18 years of age 2. Having a clinical and radiological diagnosis of non-cystic fibrosis bronchiectasis 3. Absence of cognitive impairment (MMT\>24) 4. Being clinically stable (not having experienced any exacerbation in the last 4 weeks) Exclusion Criteria: 1. Presence of any disease that may affect compliance with exercise (Unstable angina (within the last month), recent myocardial infarction (heart attack), uncontrolled arrhythmias, severe aortic stenosis, decompensated heart failure, severe pulmonary hypertension, acute respiratory tract infection, severe hypoxemia at rest (\<85%), orthopedic or neurological problems that impede walking, severe anemia, acute infections, very high resting blood pressure (systolic \>180-200 mmHg, diastolic \>100-110 mmHg), psychological issues, etc.) 2. Smoking 3. Chronic alcoholism that may affect exercise safety (More than 1 drink per day on average for women, more than 2 drinks per day on average for men (1 standard drink ≈ 10-14 g of alcohol) 4. Presence of any respiratory tract disease other than bronchiectasis 5. After incremental shuttle walk test arterial oxygen saturation \<80% 6. Participation in a structured exercise program within the last 6 months

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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Contacts and locations

Locations

  • Gulhane Faculty of Physiotherapy and Rehabilitation

    RECRUITING

    Ankara, Keçiören, 06018, Turkey (Türkiye)

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