Could a simple oxygen device improve brain death diagnosis?
NCT ID NCT07640009
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether high-flow humidified oxygen (HHFO) works as well as continuous positive airway pressure (CPAP) for keeping oxygen levels stable during the apnea test, which is used to confirm brain death. The study involves 28 adult intensive care patients who meet all criteria for clinical brain death. Each patient undergoes two apnea tests—one with HHFO and one with CPAP—to compare how well each method maintains oxygenation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-flow humidified oxygen (HHFO)
What this could lead to
If HHFO works as well as CPAP, it could offer a simpler, safer way to perform apnea tests during brain death diagnosis, potentially improving organ preservation for donation.
What could go wrong
This is a small, early-stage study with only 28 participants, so results may not apply broadly. The trial compares two methods but does not test a new treatment or cure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Chru de Tours
Tours, France
Contact Email: •••••@•••••
Contact
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Chu Angers
Angers, France
Contact Email: •••••@•••••
Contact
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Chu Orleans
Orléans, France
Contact Email: •••••@•••••
Contact
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Chu de Nantes
Nantes, France
Contact
Contact Email: •••••@•••••