Could a simple oxygen device improve brain death diagnosis?
NCT ID NCT07640009
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This trial tests whether high-flow humidified oxygen (HHFO) works as well as continuous positive airway pressure (CPAP) for keeping oxygen levels stable during the apnea test, which is used to confirm brain death. The study involves 28 adult intensive care patients who meet all criteria for clinical brain death. Each patient undergoes two apnea tests—one with HHFO and one with CPAP—to compare how well each method maintains oxygenation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- High-flow humidified oxygen (HHFO)
- What this could lead to
- If HHFO works as well as CPAP, it could offer a simpler, safer way to perform apnea tests during brain death diagnosis, potentially improving organ preservation for donation.
- What could go wrong
- This is a small, early-stage study with only 28 participants, so results may not apply broadly. The trial compares two methods but does not test a new treatment or cure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chru de Tours
Tours, France
-
Chu Angers
Angers, France
-
Chu Orleans
Orléans, France
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Chu de Nantes
Nantes, France
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