Study of hernia repair methods halted early – what we know so far

NCT ID NCT04695171

First seen Feb 28, 2026 · Last updated Jun 23, 2026 · Updated 22 times

Summary

This registry tracked 336 patients who had surgery for a large hiatal hernia (over 3 cm) either with the LINX magnetic device or a fundoplication procedure. The goal was to see how often the hernia came back over the long term. The study was terminated early, so the full picture is unclear, but it may still offer clues about which approach works better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • East Carolina University

    Greenville, North Carolina, 27858, United States

  • Esophageal Institute

    Pittsburgh, Pennsylvania, 15224, United States

  • Institute of Esophageal and Reflux Surgery

    Lone Tree, Colorado, 80124, United States

  • Keck Medical Center of USC

    Los Angeles, California, 90033, United States

  • South Florida Reflux Center

    Coral Springs, Florida, 33065, United States

  • University of Texas

    Austin, Texas, 78712, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LINX Reflux Management System (magnetic bead implant) or fundoplication surgery

What this could lead to

If successful, this could help doctors choose the best surgical option to prevent hernia recurrence in patients with large hiatal hernias.

What could go wrong

The study was terminated early, so results may be incomplete. It only looks back at past surgeries, not a controlled experiment, so findings may be less reliable.

Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease hiatus hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.