New oxygen device may make endoscopy safer for the sickest patients

NCT ID NCT07252102

Recruiting now Symptom relief Sponsor: Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a high-flow nasal cannula (HFNC) can prevent dangerous drops in oxygen levels during sedated gastrointestinal endoscopy in critically ill patients. Researchers will compare HFNC with standard nasal oxygen in 450 adults with serious health conditions. The goal is to see if HFNC reduces the chance of hypoxia and other breathing problems during the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high-flow nasal cannula oxygen (device)
What this could lead to: If it works, this could provide a safer way to perform endoscopy in critically ill patients, reducing the risk of dangerously low oxygen levels.
What could go wrong: This is a relatively small, early-stage trial. The device may not reduce hypoxia significantly, and results may not apply to all critical patients. Risks include nasal discomfort or injury from the high-flow device.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Hypoxia polyp of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL DYSFUNCTION LIVER CIRRHOSIS POLYPS OF COLON

Contacts and locations

Locations

Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center
RECRUITING

Shenzhen, Guangdong, 518116, China
Shenzhen Hospital of Southern Medical University
RECRUITING

Shenzhen, Guangdong, 518000, China
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310000, China

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