New pill targets genetic driver in multiple advanced cancers

NCT ID NCT06760819

Summary

This study is testing an oral pill called BAY2927088 for people with advanced solid tumors that have a specific genetic change (HER2 mutation). The goal is to see if the pill can shrink tumors and control the cancer's growth. About 111 adults with cancers like colorectal, breast, or bladder cancer will take the pill daily in repeating cycles until their cancer worsens or side effects occur.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aarhus University Hospital - Oncology Department

    RECRUITING

    Aarhus N, Central Jutland, 8200, Denmark

  • Aichi Cancer Center Hospital

    RECRUITING

    Nagoya, Aichi-ken, 464-8681, Japan

  • Asan Medical Center | Oncology

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 05505, South Korea

  • Azienda USL IRCCS di Reggio Emilia_Arcispedale Santa Maria Nuova - S.C. Oncologia Provinciale

    RECRUITING

    Reggio Emilia, 42123, Italy

  • Beijing Cancer Hospital - Oncology Department

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

  • Brigette Harris Cancer Pavilion at Henry Ford Cancer Center - Detroit

    WITHDRAWN

    Detroit, Michigan, 48202, United States

  • CHU Brest - Hopital La Cavale Blanche - service oncologie medicale

    RECRUITING

    Brest, Brittany Region, 29200, France

  • Centre Hospitalier Lyon Sud - Service oncologie medicale

    RECRUITING

    Pierre-Bénite, Auvergne-Rhône-Alpes, 69310, France

  • Centre Oscar Lambret - Service Oncologie

    RECRUITING

    Lille, Hauts-de-France, 59000, France

  • City of Hope - Duarte Cancer Center

    RECRUITING

    Duarte, California, 91010, United States

  • Cleveland Clinic - Oncology Department

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Clinica Universidad de Navarra | Madrid | Oncologia

    RECRUITING

    Madrid, Navarre, 28027, Spain

  • Dana-Farber Cancer Institute - Oncology Department

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Florida Cancer Specialists & Research Institute - Fort Myers Cancer Center - Gladiolus

    RECRUITING

    Fort Myers, Florida, 33908, United States

  • Fondazione IRCCS Istituto Nazionale dei Tumori - S. C. Oncologia Medica 1

    RECRUITING

    Milan, 20133, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Oncologia Medica

    RECRUITING

    Roma, 00168, Italy

  • Fudan University Shanghai Cancer Center - Oncology Department

    RECRUITING

    Shanghai, 200000, China

  • Gynecology Oncology clinic at UW Medical Center - Montlake

    WITHDRAWN

    Seattle, Washington, 98195, United States

  • Hokkaido University Hospital

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Hopitaux Universitaires de Geneve - Oncology Department

    RECRUITING

    Geneva, 1205, Switzerland

  • Hospital Universitari Vall D Hebron | Oncologia Medica

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario Fundacion Jimenez Diaz | Oncologia Medica

    RECRUITING

    Madrid, 28040, Spain

  • Hunan Cancer Hospital - Oncology Department

    RECRUITING

    Changsha, Hunan, 410013, China

  • ICM - Institut du Cancer de Montpellier - Val d'Aurelle - CIPP

    RECRUITING

    Montpellier, Occitanie, 34298, France

  • ICON Cancer Centre - Southport

    RECRUITING

    Southport, Queensland, 4215, Australia

  • Inselspital Bern - Universitätsklinik für Medizinische Onkologie

    RECRUITING

    Bern, 3010, Switzerland

  • Institut Bergonie - Unicancer Nouvelle Aquitaine - Service Oncologie medicale

    RECRUITING

    Bordeaux, Nouvelle-Aquitaine, 33000, France

  • Institut Catala D'oncologia | Hospitalet | Oncologia

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • Institut Gustave Roussy - Departement d'Innovation Therapeutique et d'Essais Precoces (DITEP)

    RECRUITING

    Villejuif, Île-de-France Region, 94805, France

  • Instituto Oncologico Dr. Rosell S.L. | Oncologia

    RECRUITING

    Barcelona, 08028, Spain

  • Istituto Europeo di Oncologia s.r.l - Ginecologia Oncologica Medica

    RECRUITING

    Milan, 20141, Italy

  • Kindai University Hospital

    RECRUITING

    Sakai, Osaka, 590-0197, Japan

  • Macquarie University Hospital - Oncology Department

    RECRUITING

    Sydney, New South Wales, 2109, Australia

  • McGill University Health Centre - Glen Site

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • NSW Health - Blacktown Hospital

    RECRUITING

    Blacktown, New South Wales, 2148, Australia

  • National Cancer Center Hospital

    RECRUITING

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East (NCCHE) - Kashiwa Campus

    RECRUITING

    Kashiwa, Chiba, 277-8577, Japan

  • Odense University Hospital - Oncology Department

    RECRUITING

    Odense, Region Syddanmark, 5000, Denmark

  • Peking University First Hospital - Oncology Department

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

  • Princess Margaret Cancer Centre - University Health Network - Department of Medical Oncology and Hematology

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

  • Profound Research -OMG - TriAtria Cancer Center

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

  • Queen Elizabeth II Health Sciences Centre - Victoria General Site

    RECRUITING

    Halifax, Nova Scotia, B3H 1V7, Canada

  • Rigshospitalet - Kræftbehandling

    RECRUITING

    Copenhagen, Capital Region, 2100, Denmark

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Samsung Medical Center - Oncology Department

    RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 3080, South Korea

  • Severance Hospital, Yonsei University Health System - Oncology Department

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03722, South Korea

  • Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine - Oncology Department

    RECRUITING

    Hangzhou, Zhejiang, 310016, China

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Koto-ku, Tokyo, 135-8550, Japan

  • The University of Texas MD Anderson Cancer Center - Texas Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

  • UAB O'Neal Comprehensive Cancer Center - The Kirklin Clinic of UAB Hospital

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • UW Health Carbone Cancer Center

    RECRUITING

    Madison, Wisconsin, 53792, United States

  • Univestitätsspital Zürich (USZ)

    RECRUITING

    Zurich, 8091, Switzerland

  • Zhongshan Hospital, Fudan University - Oncology Department

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

Conditions

Explore the condition pages connected to this study.