New immune therapy aims to knock out lingering hepatitis b
NCT ID NCT05343481
Summary
This study is testing whether a new two-part immunotherapy called VTP-300, given with a low dose of an existing drug (nivolumab), can help the body's immune system better control chronic Hepatitis B. It involves 120 adults whose virus is already suppressed by daily pills. The main goal is to see if this combination can significantly reduce a key marker of the virus in the blood over six months.
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Contacts and locations
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Locations
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Bamrasnaradura Infectious Diseases Institute
Nonthaburi, 11000, Thailand
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Chang Gung Memorial Hospital Kaohsiung
Kaohsiung City, Taiwan
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Chia-Yi Christian Hospital
Chiayi City, 60002, Taiwan
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China Medical University Hospital
Taichung, 404332, Taiwan
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Chulabhorn Hospital
Bangkok, 10210, Thailand
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Dalin Tzu Chi Hospital
Chiayi City, Taiwan
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HIV Netherlands-Australia-Thailand Research Collaboration
Bangkok, Thailand
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Hospital For Tropical Diseases
Bangkok, Thailand
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Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, 807, Taiwan
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King Chulalongkorn Memorial Hospital
Bangkok, 10330, Thailand
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Linkou Chang Gung Memorial Hospital
Taoyuan, 333, Taiwan
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Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, 50200, Thailand
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National Cheng Kung University Hospital
Tainan, 704, Taiwan
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National Taiwan University Hospital
Taipei, Taiwan
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Prince Of Wales Hospital
Hong Kong, Hong Kong
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Queen Mary Hospital
Hong Kong, Hong Kong
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Research Institute For Health Sciences
Chiang Mai, Thailand
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Srinagarind Hospital
Khon Kaen, Thailand
Conditions
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