New hope for kids with hepatitis b: testing a promising drug

NCT ID NCT02932150

Summary

This study aims to test the safety and effectiveness of a medication called tenofovir alafenamide (TAF) for children and teenagers with chronic hepatitis B. It will enroll 150 participants to compare the drug against a placebo for 24 weeks, followed by longer-term monitoring. The main goals are to see if the drug reduces the virus in the blood, is safe for young people, and to determine the right dose for children.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AOU di Bologna - Policlinico S. Orsola Malpighi - Dipartimento Malattic dell'Apparato Digerente e Medicina Intema

    WITHDRAWN

    Bologna, 40138, Italy

  • AdventHealth Medical Group

    WITHDRAWN

    Orlando, Florida, 32803, United States

  • All India Institute of Medical Sciences

    RECRUITING

    New Delhi, 110029, India

  • American Research Corporation at Texas Liver Institute

    COMPLETED

    San Antonio, Texas, 78215, United States

  • Asan Medical Center

    COMPLETED

    Seoul, 5505, South Korea

  • Auckland Clinical Studies Limited

    WITHDRAWN

    Auckland, 1010, New Zealand

  • BC Children's Hospital

    WITHDRAWN

    Vancouver, V6H3V4, Canada

  • Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou

    RECRUITING

    Taoyuan District, 33305, Taiwan

  • Chang Gung Medical Foundation, Kaohsiung Chang Gung Memorial Hospital

    ACTIVE_NOT_RECRUITING

    Kaohsiung City, 83301, Taiwan

  • Children's Healthcare of Atlanta

    WITHDRAWN

    Atlanta, Georgia, 30322, United States

  • Children's Hospital & Medical Center

    WITHDRAWN

    Omaha, Nebraska, 68198, United States

  • Children's Hospital Colorado

    ACTIVE_NOT_RECRUITING

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Los Angeles

    ACTIVE_NOT_RECRUITING

    Los Angeles, California, 90027, United States

  • Children's Medical Center

    WITHDRAWN

    Dallas, Texas, 75235, United States

  • Children's Mercy Hospital

    RECRUITING

    Kansas City, Missouri, 64108, United States

  • Cincinnati Children's Hospital Medical Center

    ACTIVE_NOT_RECRUITING

    Cincinnati, Ohio, 45229, United States

  • Cliniques Universitaires Saint-LUC UCL

    COMPLETED

    Brussels, 1200, Belgium

  • Cook Children's Medical Center

    COMPLETED

    Fort Worth, Texas, 76104, United States

  • Federal Budgetary Institution of Science "Central Scientific-Research Institute of Epidemiology"

    WITHDRAWN

    Moscow, 111123, Russia

  • Federal Budgetary Scientific Institution Pasteur St. Petersburg Scientific Research Institute of Epidemiology and Microbiology

    WITHDRAWN

    Saint Petersburg, 197101, Russia

  • Federal Research Centre of Nutrition, Biotechnology and Food Safety

    COMPLETED

    Moscow, 115446, Russia

  • Federal State-Financed Institution Pediatric Research and Clinical Center for Infectious Diseases

    COMPLETED

    Saint Petersburg, 197022, Russia

  • GCS Medical Hospital & Research Center

    WITHDRAWN

    Ahmedabad, 380025, India

  • Indiana University School of Medicine

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Institute of Post Graduation Medical Education & Research

    RECRUITING

    Kolkata, 700020, India

  • Institutul National de Boli Infectioase "Prof.Dr. Matei Bals"

    ACTIVE_NOT_RECRUITING

    Bucharest, 21105, Romania

  • Johns Hopkins University

    ACTIVE_NOT_RECRUITING

    Baltimore, Maryland, 21287, United States

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    ACTIVE_NOT_RECRUITING

    Kaohsiung City, 807, Taiwan

  • Khalatkar Hospital

    RECRUITING

    Nagpur, 440009, India

  • Krasnoyarsk Regional Clinical Center of Maternal and Child Welfare

    WITHDRAWN

    Krasnoyarsk, 660074, Russia

  • Kyungpook National University Hospital

    COMPLETED

    Daegu, 41944, South Korea

  • LTMMC & LTMG Hospital

    ACTIVE_NOT_RECRUITING

    Mumbai, 400022, India

  • Limited Medical Company Hepatolog

    COMPLETED

    Tolyatti, 445009, Russia

  • M. V Hospital and Research Center

    RECRUITING

    Lucknow, 226003, India

  • Midas Multispecility Hospital PVT. LTD.

    WITHDRAWN

    Nagpur, 440010, India

  • Monroe Carell Jr. Children's Hospital at Vanderbilt

    COMPLETED

    Nashville, Tennessee, 37232, United States

  • Nandita Hospital and Research Centre

    WITHDRAWN

    Nagpur, 440003, India

  • National Cheng Kung University Hospital

    COMPLETED

    Tainan, 704, Taiwan

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100, Taiwan

  • Nationwide Children's Hospital

    COMPLETED

    Columbus, Ohio, 43205, United States

  • Pratha Gastro Liver Center

    WITHDRAWN

    Kanpur, 208012, India

  • Prince of Wales Hospital

    COMPLETED

    Shatin, Hong Kong

  • Rady Childrens Hospital

    ACTIVE_NOT_RECRUITING

    San Diego, California, 92123, United States

  • Republican Clinical Hospital of Infectious Diseases named after A.F. Agafonov

    COMPLETED

    Tatarstan, 420110, Russia

  • SIDS Hospital and Research Centre

    RECRUITING

    Surat, 395002, India

  • SR Kalla Memorial Gastro And General Hospital

    WITHDRAWN

    Jaipur, 302001, India

  • Samsung Medical Center

    RECRUITING

    Seoul, 6351, South Korea

  • Samvedna Hospital

    RECRUITING

    Varanasi, 221005, India

  • Scientific Center of Children's Health of the Ministry of Health of the Russian Federation

    WITHDRAWN

    Moscow, 119991, Russia

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

  • Seoul National University Hospital

    WITHDRAWN

    Seoul, 03080, South Korea

  • Seth GS Medical College and KEM Hospital

    RECRUITING

    Mumbai, 400012, India

  • Severance Hospital, Yonsei University Health System

    WITHDRAWN

    Seoul, South Korea

  • Spitalul Grigore Alexandrescu-Sectia Pediatrie III

    ACTIVE_NOT_RECRUITING

    Bucharest, 11743, Romania

  • Taipei Mackay Memorial Hospital

    WITHDRAWN

    Taipei, 104, Taiwan

  • Texas Children's Hospital - Main Hospital

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • The Children's Hospital at Montefiore

    COMPLETED

    The Bronx, New York, 10467, United States

  • The Hospital for Sick Children

    WITHDRAWN

    Toronto, M5G 1X8, Canada

  • University of California, San Francisco (UCSF)

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94158, United States

  • University of Miami/Schiff Center for Liver Diseases

    WITHDRAWN

    Miami, Florida, 33136, United States

  • University of Minnesota Masonic Children's Hospital

    WITHDRAWN

    Minneapolis, Minnesota, 55455, United States

  • West Virginia University Hospitals

    WITHDRAWN

    Morgantown, West Virginia, 26506, United States

Conditions

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