New hope for hepatitis d: experimental drug enters final testing phase
NCT ID NCT07309380
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests a drug called hepalatide (L47) in 150 people with chronic hepatitis D, a serious liver disease. Participants receive either the drug or a placebo daily for 48 weeks. The goal is to see if hepalatide can lower virus levels and normalize liver enzymes. After the main phase, all participants can choose to receive the drug in an open-label follow-up.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hepalatide (also called L47)
- What this could lead to
- If successful, this could provide a new treatment option for chronic hepatitis D, potentially controlling the virus and improving liver function.
- What could go wrong
- This is an early-stage Phase 3 trial with only 150 participants. The drug may not work better than placebo, and side effects are possible. Long-term benefits are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
First Hospital of Jilin University
Changchun, Jilin, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.