New combo pill aims to simplify diabetes care from day one
NCT ID NCT06888050
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a once-daily combination of henagliflozin and metformin works better than standard metformin alone in people newly diagnosed with type 2 diabetes. 268 adults will take either the combo pill or metformin twice a day for 24 weeks. Researchers will measure changes in blood sugar, weight, and how many achieve diabetes remission.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Henagliflozin proline and metformin hydrochloride extended-release tablets
- What this could lead to
- If successful, this could show that a once-daily combination pill controls blood sugar and weight better than standard metformin alone in early diabetes.
- What could go wrong
- This is a Phase 4 study, so the drugs are already approved; the main question is whether the combo is significantly better. Side effects like urinary infections or dehydration are possible with henagliflozin.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zhejiang Provincial People's Hospital
RECRUITINGHangzhou, Zhejiang, 310000, China