New hope for young boys with rare bleeding disorder

NCT ID NCT02141074

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

Summary

This trial tested a new, long-acting version of a missing clotting protein (Factor IX) in young boys with severe hemophilia B who had little to no prior treatment. The goal was to see if regular injections could safely prevent bleeding episodes and effectively treat bleeds when they occurred. Researchers measured how well it worked and checked for any safety issues, especially the development of antibodies that could block the treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

'Ippokrateio' General Hospital of Thessaloniki

Thessaloniki, 54642, Greece
,,Louis Ţurcanu'' Emergency Hospital for Children

Timișoara, Timiș County, 300011, Romania
1st Paediatric Department, Fundeni Clinical Institute

Bucharest, 022328, Romania
Aghia Sophia Childrens' Hospital

Athens, GR-11527, Greece
Ap-Hp-Hopital de Bicetre-1

Le Kremlin-Bicêtre, 94275, France
Augusta University

Augusta, Georgia, 30912, United States
Beni Messous Hospital Issaad Hassani

Algiers, 16000, Algeria
Birmingham Children's Hospital

Birmingham, B4 6NH, United Kingdom
CHU Estaing

Clermont-Ferrand, 63003, France
CHU Haute Pierre

Strasbourg, 67098, France
Centre Hospitalier Universitaire de Nantes-Hopital Hotel-Dieu

Nantes, 44093, France
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou

Rennes, 35033, France
Centro Hospitalar Lisboa Norte-HSM

Lisbon, 1649-035, Portugal
Centro Medico Nacional SXXI-Hospital de Pediatria, IMSS

Mexico City, México, D.F., 06720, Mexico
Changhua Christian Hospital

Changhua, 500, Taiwan
Changhua Christian Hospital_Hematology Dept.

Changhua, 500, Taiwan
Children's Hosp-New Orleans

New Orleans, Louisiana, 70118-5720, United States
Children's Hospital Los Angeles - Endocrinology

Los Angeles, California, 90027, United States
Children's Hsptl Of The Kings

Norfolk, Virginia, 23507, United States
China Medical University Children's Hospital

Taichung, 40447, Taiwan
China Medical University Hospital - Children Building

Taichung, 40447, Taiwan
Coagulation Research Center

Duisburg, 47051, Germany
Dayton Children Hemostati Ctr

Dayton, Ohio, 45404, United States
Dipartimento di Ematologia Univ. Firenze

Florence, 50134, Italy
HZRM Haemophilie-Zentrum Rhein Main GmbH

Frankfurt am Main, 60596, Germany
Hamltn Hth Sci/McMstr Child Hosp

Hamilton, Ontario, L8N 3Z5, Canada
Hope for Kids

Macon, Georgia, 31201, United States
Hospital La Fe - Endocrinología y Nutrición

Valencia, 46026, Spain
Hospital Pulau Pinang_Georgetown, Penang

George Town, Pulau Pinang, 10450, Malaysia
Hospital Sant Joan de Déu

Esplugues Llobregat, 08950, Spain
Hospital Tengku Ampuan Afzan

Kuantan, Pahang, 25100, Malaysia
Hospital Tengku Ampuan Rahimah

Klang, Selangor, 41200, Malaysia
Hospital Universitario Dr. José Eleuterio González_Monterrey

Monterrey, Nuevo León, 64460, Mexico
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital de Pediatría S.A.M.I.C. "Prof. Dr. Juan P. Garrahan

CABA, C1245AAM, Argentina
IRCCS Meyer Firenze

Florence, 50139, Italy
Institute for Mother and Child Health Care of Serbia

Belgrade, 11070, Serbia
Institute of blood pathology and transfusion medicine of NAMSU - General and haematol. surgery

Lviv, 79044, Ukraine
John Radcliffe Hospital

Oxford, OX3 9DU, United Kingdom
Johns Hopkins University_Baltimore_3

Baltimore, Maryland, 21205, United States
Kanagawa Children's Medical Center _ Hematology / Oncology

Kanagawa, 232-8555, Japan
Kaohsiung Medical University Chung-Ho Memorial Hospital_Dept of Pediatrics

Kaohsiung City, 807, Taiwan
Kent and Canterbury Hospital - Kent Haemophilia and Thrombosis Centre

Canterbury, CT1 3NG, United Kingdom
King Chulalongkorn Memorial Hospital_Pediatric Hematology-Oncology

Bangkok, 10330, Thailand
Klinikum Klagenfurt am Wörthersee (LKH Klagenfurt)

Klagenfurt, 9020, Austria
LKH Salzburg- Univ. Klinik f. Kinder- und Jugendheilkunde

Salzburg, 5020, Austria
Lady Cilento Children's Hospital

South Brisbane, Queensland, 4101, Australia
Landes-Frauen und Kinderklinik Linz

Linz, 4020, Austria
Leicester Royal Infirmary - Haemostasis & Thrombosis Unit

Leicester, LE1 5WW, United Kingdom
Maharaj Nakorn Chiang Mai Hospital _Pediatric Hematology and Oncology

Chiang Mai, 50200, Thailand
Med. Univ. Graz -Klinische Abteilung f. Allgemeine Pädiatrie

Graz, 8036, Austria
Medical University Of SC

Charleston, South Carolina, 29425, United States
Miller Children's Hospital Long Beach

Long Beach, California, 90806, United States
Nagoya University Hospital_Blood Transfusion

Aichi, 466-8560, Japan
National Blood Centre

Kuala Lumpur, 50400, Malaysia
National Center for Child Health and Development_Hematology

Tokyo, 157-8535, Japan
National Taiwan University Children's Hospital

Taipei, 100, Taiwan
Nemours Chld Clnc Jacksonville

Jacksonville, Florida, 32207, United States
North Shore Long Island Jewish Medical Center

New Hyde Park, New York, 11040, United States
Novant Hlth Vasc Ins Charlotte

Charlotte, North Carolina, 28204, United States
Ogikubo Hospital_Pediatries & Blood

Tokyo, 167-0035, Japan
Ordination Prof. Zwiauer

Sankt Pölten, A 3100, Austria
Penn State MS Hershey Med Ctr

Hershey, Pennsylvania, 17033, United States
Radboudumc

Nijmegen, 6525 GA, Netherlands
Ramathibodi Hospital_Paediatrics

Bangkok, 10400, Thailand
Royal Children's Hospital

Parkville, Victoria, 3052, Australia
Royal Hospital for Children

Glasgow, G51 4TF, United Kingdom
Royal Manchester Children's Hospital

Manchester, M13 9WL, United Kingdom
SI Institute of Urgent and Recovery Surgery - Haematology

Donetsk, 83045, Ukraine
Saitama Children's Med Centre_Hematology-Oncology

Saitama, 330-8777, Japan
Sanatorio Mayo Privado S.A

Córdoba, X5000FAL, Argentina
Shands Hospital at the University of Florida

Gainesville, Florida, 32610, United States
Sheba MC - The Israeli National Hemophilia Center

Tel Litwinsky, 52621, Israel
Shizuoka Children's Hospital, Hematology-Oncology

Shizuoka, 420-8660, Japan
St Christopher Hosp for Child

Philadelphia, Pennsylvania, 19134, United States
St Thomas' Hospital - Haemostasis and Thrombosis Centre

London, SE1 7EH, United Kingdom
St. Luke's Mountain States Tumor Institute

Boise, Idaho, 83712, United States
The Hospital for Sick Children

Toronto, Ontario, M5G 1X8, Canada
ULS São João, E.P.E.

Porto, 4200-319, Portugal
UMHAT Sveti Georgi EAD, Plovdiv, Clinic of Pediatrics

Plovdiv, 4002, Bulgaria
Univ Hosp Cleveland Med Ctr

Cleveland, Ohio, 44106, United States
Univ of NE Med Center_Omaha

Omaha, Nebraska, 68198-6828, United States
Univ of Utah Primary Children's Hospital

Salt Lake City, Utah, 84113, United States
University Children's Hospital Tirsova

Belgrade, 11000, Serbia
University Hospital Saadna Abdenour of Setif

Sétif, 19000, Algeria
University Of Iowa

Iowa City, Iowa, 52242, United States
University of North Carlolina-Chapel Hill

Chapel Hill, North Carolina, 27514, United States
University of Virginia Children's Hospital

Charlottesville, Virginia, 22903, United States
Universitätsklinik Kinder-Jugendheilkunde Innsbruck

Innsbruck, 6020, Austria
Universitätsklinik für Kinder- und Jugendheilkunde

Vienna, A 1090, Austria
Universitätsklinikum Bonn - Institut für Experimentelle Hämatologie

Bonn, 53127, Germany
Vanderbilt Hemostasis Thrombosis Clinic

Nashville, Tennessee, 37232, United States
Werlhof-Institut

Hanover, 30159, Germany

Conditions

Explore the condition pages connected to this study.

CONGENITAL BLEEDING DISORDER HAEMOPHILIA B