New hope for kids with severe bleeding disorder: advanced treatment shows promise

NCT ID NCT04759131

Completed Disease control Sponsor: Bioverativ, a Sanofi company Source: ClinicalTrials.gov ↗

Summary

This study tested a new, long-acting factor VIII replacement drug called BIVV001 in children under 12 with severe hemophilia A. The main goal was to see if it was safe and effective at preventing and treating bleeding episodes over a year of treatment. Researchers also looked at how it affected joint health, quality of life, and its use during surgery.

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Contacts and locations

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Locations

Children's Healthcare of Atlanta-Site Number:8400019

Atlanta, Georgia, 30322, United States
Children's Hospital Los Angeles-Site Number:8400006

Los Angeles, California, 90027, United States
Children's Hospital Of Wisconsin-Site Number:8400005

Milwaukee, Wisconsin, 53226-0509, United States
Childrens Hospital Of Columbus-Site Number:8400012

Columbus, Ohio, 43205, United States
Cincinnati Children's Hospital Medical Center-Site Number:8400008

Cincinnati, Ohio, 45206, United States
East Carolina University/Brody Medical Sciences Building-Site Number:8400015

Greenville, North Carolina, 27834, United States
Investigational Site Number :0360001

Westmead, New South Wales, 2145, Australia
Investigational Site Number :0360002

South Brisbane, Queensland, 4101, Australia
Investigational Site Number :1240001

Toronto, Ontario, M5G 1X8, Canada
Investigational Site Number :1240002

Ottawa, Ontario, K1H 8L1, Canada
Investigational Site Number :1240003

London, Ontario, N6A 4G5, Canada
Investigational Site Number :1240004

Hamilton, Ontario, L8N 3Z5, Canada
Investigational Site Number :1580001

Taichung, 402, Taiwan
Investigational Site Number :1580002

Taipei, 10002, Taiwan
Investigational Site Number :1580003

Taichung, 407, Taiwan
Investigational Site Number :1580004

Taipei, 11031, Taiwan
Investigational Site Number :2500001

Le Kremlin-Bicêtre, 94275, France
Investigational Site Number :2500003

Lille, 59037, France
Investigational Site Number :2500004

Bron, 69500, France
Investigational Site Number :2760001

Frankfurt am Main, 60590, Germany
Investigational Site Number :2760002

München, 80337, Germany
Investigational Site Number :3480005

Pécs, 7623, Hungary
Investigational Site Number :3720001

Dublin, D12 N512, Ireland
Investigational Site Number :3800001

Milan, 20121, Italy
Investigational Site Number :3800002

Naples, 80123, Italy
Investigational Site Number :5280001

Utrecht, 3584 CX, Netherlands
Investigational Site Number :5280002

Amsterdam, 1105 AZ, Netherlands
Investigational Site Number :7240001

Madrid, Madrid, Comunidad de, 28046, Spain
Investigational Site Number :7240002

Esplugues de Llobregat, Catalunya [Cataluña], 08950, Spain
Investigational Site Number :7520001

Malmo, 20502, Sweden
Investigational Site Number :7560001

Zurich, 8032, Switzerland
Investigational Site Number :7920001

Istanbul, 34390, Turkey (Türkiye)
Investigational Site Number :7920003

Izmir, TR-35100, Turkey (Türkiye)
Investigational Site Number :7920004

Antalya, 07059, Turkey (Türkiye)
Investigational Site Number :8260001

London, WC1N3JH, United Kingdom
Investigational Site Number :8260003

Birmingham, B4 6NH, United Kingdom
NY Presbyterian - Weill Cornell Medical Center-Site Number:8400020

New York, New York, 10021, United States
Rush University Medical Center-Site Number:8400001

Chicago, Illinois, 60612-3833, United States
University of Florida-Site Number:8400009

Gainesville, Florida, 32610, United States
University of Iowa Hospitals and Clinics-Site Number:8400002

Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.

HEMOPHILIA A