Could a flower extract help heal irritated skin faster?

NCT ID NCT07676253

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether a cream made with Helichrysum italicum (Immortelle) extract can help heal irritated skin and restore the skin barrier better than a plain moisturizer. Healthy volunteers will have a small patch of skin irritated with a mild soap, then apply the Immortelle cream, a placebo cream, or nothing to different spots. Researchers will measure skin moisture, water loss, and redness over several days to see if the extract provides extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Helichrysum italicum extract cream

What this could lead to

If it works, this could point toward a natural ingredient for soothing skin irritation and speeding up skin barrier repair.

What could go wrong

This is a very small, early study in healthy volunteers with artificially induced irritation, so results may not apply to real-world skin conditions. The extract may offer no extra benefit over a standard moisturizer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

irritant dermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Split School of Medicine

    RECRUITING

    Split, 21000, Croatia

    Contact Phone: •••-•••-•••• Email: •••••@•••••