Massive study probes heart risks of popular Weight-Loss pill

NCT ID NCT06098079

Recruiting now Disease control Sponsor: Currax Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This large study aims to find out if a weight loss medication (Contrave/Mysimba) increases the risk of serious heart problems like heart attacks or strokes. It will enroll 8,600 overweight or obese adults who already have a higher risk for heart disease. Participants will be randomly assigned to receive either the real medication or a placebo (sugar pill), and all will also receive standard advice on diet and exercise.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

ABMED Clinical Research
ACTIVE_NOT_RECRUITING

Cape Coral, Florida, 33914, United States
AMR - El Dorado
RECRUITING

El Dorado, Kansas, 67042, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
AMR Mobile
RECRUITING

Mobile, Alabama, 36608, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
AMR New Orleans
TERMINATED

New Orleans, Louisiana, 70119, United States
AMR Norfolk
RECRUITING

Norfolk, Virginia, 23502, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
AMR Wichita East
RECRUITING

Wichita, Kansas, 67207, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
AMR Wichita West
TERMINATED

Wichita, Kansas, 67205, United States
Accel Research Sites (ARSN) - Neurostudies
RECRUITING

Decatur, Georgia, 30030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Accel Research Sites Network
RECRUITING

Birmingham, Alabama, 35216, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Accel Research Sites Network - Edgewater
TERMINATED

Edgewater, Florida, 32132, United States
ActivMed Practices and Research
TERMINATED

Portsmouth, New Hampshire, 03801, United States
Activmed Practices and Research, Inc
RECRUITING

Methuen, Massachusetts, 01844, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Advanced Cardiovascular Specialists/NextStage Clinical Research
RECRUITING

Beaumont, Texas, 77702, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Advanced Clinical Research
RECRUITING

Miami, Florida, 33156, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Advanced Clinical Research Atlanta
RECRUITING

Atlanta, Georgia, 30309, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
All-American Orthopedics-NextStage Clinical Research
RECRUITING

Houston, Texas, 77058, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Altus Research
RECRUITING

Lake Worth, Florida, 33461, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Avacare
RECRUITING

Las Vegas, Nevada, 89102, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Axces Research Group
TERMINATED

Santa Fe, New Mexico, 87505, United States
Best Choice Medical and Research Services
RECRUITING

Pembroke Pines, Florida, 33024, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Biscayne Clinical Research Inc
RECRUITING

North Miami, Florida, 33169, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Bolanos Clnical Research
RECRUITING

Pembroke Pines, Florida, 33028, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cardiovascular Consultants/NextStage Clinical Research
TERMINATED

Glendale, Arizona, 85306, United States
Century Research
TERMINATED

Miami, Florida, 33173, United States
Charlottesville Medical Research
RECRUITING

Charlottesville, Virginia, 22911, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Chemidox Clinical Trials Inc.
RECRUITING

Lancaster, California, 93534, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Clay Platte Family Medicine
RECRUITING

Kansas City, Missouri, 64151, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Clincept Clinical Research
RECRUITING

Columbus, Georgia, 31904, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Coastal Carolina Research Center
RECRUITING

North Charleston, South Carolina, 29405, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Conveinent Medical Research
RECRUITING

Hialeah, Florida, 33013, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cordova Research Institute
RECRUITING

Sweetwater, Florida, 33182, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cullman Clinical Trials
TERMINATED

Cullman, Alabama, 35055, United States
D&H Doral Research Center
RECRUITING

Doral, Florida, 33122, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
D&H Pompano Research Center, LLC
RECRUITING

Margate, Florida, 33063, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
D&H Tamarac Research Center, LLC
RECRUITING

Tamarac, Florida, 33321, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Dearborn Cardiology
TERMINATED

Dearborn, Michigan, 48126, United States
Delray Physician Center
RECRUITING

Delray Beach, Florida, 33445, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Desert Clinical Research
RECRUITING

Mesa, Arizona, 85213, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Entrust Clinical Research
RECRUITING

Miami, Florida, 33176, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Evergreen Surgical
TERMINATED

Eau Claire, Wisconsin, 54701, United States
Fiel Family & Sports Medicine CCT Research
RECRUITING

Tempe, Arizona, 85283, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
G+C Research Group
TERMINATED

Hialeah, Florida, 33010, United States
HDH Research
RECRUITING

Houston, Texas, 77022, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hatboro Medical Associates/Avacare Research
RECRUITING

Horsham, Pennsylvania, 19044, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Healix Clinical Research
RECRUITING

New Smyrna Beach, Florida, 32168, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
IMRC At Palmetto Bay
RECRUITING

Palmetto Bay, Florida, 33157, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
IMRC Fort Lauderdale
RECRUITING

Fort Lauderdale, Florida, 33316, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
ITB Research
RECRUITING

Miami, Florida, 33173, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ilumina Medical Research
RECRUITING

Kissimmee, Florida, 34744, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Indiana Medical Research Institute
RECRUITING

Merriville, Indiana, 46410, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Innovia Research Center
RECRUITING

Miramar, Florida, 33027, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
JAELEX Research
TERMINATED

Round Lake Beach, Illinois, 60073, United States
JY Research Institute
RECRUITING

Cutler Bay, Florida, 33189, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Janus Clinical Research
RECRUITING

Miami, Florida, 33186, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
LMG Research
RECRUITING

Coral Gables, Florida, 33134, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Las Vegas Clinical Trials
RECRUITING

North Las Vegas, Nevada, 89119, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Long Beach Clinical Trials
RECRUITING

Long Beach, California, 90806, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Medical Research Center Westchester
RECRUITING

Miami, Florida, 33165, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mercado Medical Practice/CCT Research
TERMINATED

Philadelphia, Pennsylvania, 19111, United States
Meridian Clinical Research - Velocity
RECRUITING

Omaha, Nebraska, 68134, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Miami Beach Clinical Research
RECRUITING

Miami Beach, Florida, 33141, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Midwest Regional Health Services
TERMINATED

Omaha, Nebraska, 68144, United States
National Institute of Clinical Research, Inc.
RECRUITING

Pomona, California, 91768, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
New Horizons Research
RECRUITING

Palmetto Bay, Florida, 33176, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
NexGen Research
RECRUITING

Lima, Ohio, 45801, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
NextStage Clinical Research - Tulsa
RECRUITING

Tulsa, Oklahoma, 74136, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
NextStage Clinical Research-Chicago
TERMINATED

Glen Ellyn, Illinois, 60137, United States
NextStage Clinical Research-Lubbock/SWAT Surgical Associates-NextStage Clinical Research
TERMINATED

Lubbock, Texas, 79410, United States
NextStage Clinical Research-Port Arthur/Gulf Coast Cardiology
RECRUITING

Port Arthur, Texas, 77642, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Olympus Clinical Research
RECRUITING

Sugarland, Texas, 77479, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Optimal Research, LLC. - Austin
RECRUITING

Austin, Texas, 78705, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Optimal Research, LLC. - Melbourne
RECRUITING

Melbourne, Florida, 32934, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Praveen K Gupta, MD/Avacare
RECRUITING

Rockville, Maryland, 20852, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Providere Research
RECRUITING

West Covina, California, 91790, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Qway Research
RECRUITING

Hialeah, Florida, 33010, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Regenerative Orthopedics and Sports Medicine- NextStage Clinical Research
TERMINATED

North Bethesda, Maryland, 20852, United States
Santa Rosa Urgent Care Primary Care/CCT Research
TERMINATED

Las Vegas, Nevada, 89119, United States
Southwest General Healthcare Center
RECRUITING

Fort Myers, Florida, 33907, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
St. Louis Medical Professionals/CCT Research
ACTIVE_NOT_RECRUITING

St Louis, Missouri, 63119, United States
Sun City Research
RECRUITING

Glendale, Arizona, 85304, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Synexus Clinical Research US, Inc. - New York
TERMINATED

New York, New York, 10017, United States
Synexus Clinical Research US, Inc. - The Villages
RECRUITING

The Villages, Florida, 32162, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Synexus Clinical Research US; Inc.
RECRUITING

Tucson, Arizona, 85741, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Synexus Clinical Research US; Inc.
RECRUITING

San Antonio, Texas, 78229, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tandem Clinical Research
NOT_YET_RECRUITING

Covington, Louisiana, 70433, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
TrialMed Birmingham (DRS)
NOT_YET_RECRUITING

Birmingham, Alabama, 35211, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Valley Vitality Ventures
RECRUITING

Manteca, California, 95350, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Chula Vista, California, 91911, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
TERMINATED

Los Angeles, California, 90057, United States
Velocity Clinical Research
RECRUITING

Valparaiso, Indiana, 46383, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Sioux City, Iowa, 51106, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Baton Rouge, Louisiana, 70809, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Covington, Louisiana, 70433, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Lafayette, Louisiana, 70508, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
TERMINATED

Slidell, Louisiana, 70458, United States
Velocity Clinical Research
RECRUITING

Gulfport, Mississippi, 39503, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Lincoln, Nebraska, 68510, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Albuquerque, New Mexico, 87107, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Binghamton, New York, 13905, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
TERMINATED

Vestal, New York, 13850, United States
Velocity Clinical Research
RECRUITING

Beachwood, Ohio, 44122, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Cincinnati, Ohio, 45246, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Anderson, South Carolina, 29621, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
TERMINATED

Charleston, South Carolina, 29414, United States
Velocity Clinical Research
RECRUITING

Columbia, South Carolina, 29204, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
RECRUITING

Gaffney, South Carolina, 29340, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research
TERMINATED

Greenville, South Carolina, 29615, United States
Velocity Clinical Research
RECRUITING

Austin, Texas, 78759, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research (New Smyrna Beach)
RECRUITING

Edgewater, Florida, 32132, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research (Providence)
RECRUITING

East Greenwich, Rhode Island, 02818, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research at Coastal Heart Medical Group
TERMINATED

Santa Ana, California, 92704, United States
Velocity Clinical Research at Pioneer Heart Institute
TERMINATED

Lincoln, Nebraska, 68506, United States
Velocity Clinical Research of Santa Ana
TERMINATED

Santa Ana, California, 92704, United States
Velocity Clinical Research, Abilene
RECRUITING

Abilene, Texas, 79606, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Cincinnati
RECRUITING

Cincinnati, Ohio, 45242, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Denver
RECRUITING

Englewood, Colorado, 80110, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Durham
RECRUITING

Durham, North Carolina, 27701, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Gardena
RECRUITING

Anderson, California, 90247, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Grand Island
RECRUITING

Grand Island, Nebraska, 68803, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Grants Pass
TERMINATED

Grants Pass, Oregon, 97527, United States
Velocity Clinical Research, Hampton
RECRUITING

Hampton, Virginia, 23666, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Huntington Park
RECRUITING

Huntington Park, California, 90255, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Kansas City
TERMINATED

Kansas City, Kansas, 66210, United States
Velocity Clinical Research, Medford
RECRUITING

Medford, Oregon, 97504, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Mobile
RECRUITING

Mobile, Alabama, 36608, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Mt. Auburn
RECRUITING

Cincinnati, Ohio, 45219, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, New Orleans
RECRUITING

New Orleans, Louisiana, 70119, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Norfolk
RECRUITING

Norfolk, Nebraska, 68701, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Phoenix
RECRUITING

Phoenix, Arizona, 85006, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Rockville
RECRUITING

Rockville, Maryland, 20854, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Salt Lake City
RECRUITING

West Jordan, Utah, 84088, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, San Bernardino
RECRUITING

San Bernardino, California, 92408, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, San Diego
RECRUITING

La Mesa, California, 91942, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Savannah
RECRUITING

Savannah, Georgia, 31406, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Spartanburg
RECRUITING

Spartanburg, South Carolina, 29303, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Suffolk, VA
RECRUITING

Suffolk, Virginia, 23435, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Union
RECRUITING

Union, South Carolina, 29379, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velocity Clinical Research, Van Nuys
ACTIVE_NOT_RECRUITING

Van Nuys, California, 91405, United States
Waco Cardiology Consultants
RECRUITING

Waco, Texas, 76712, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Wichita Surgical Specialists
RECRUITING

Wichita, Kansas, 67214, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

OBESITY