New pill aims to help heart failure patients walk farther and feel better

NCT ID NCT06991257

Recruiting now Symptom relief Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Feb 01, 2026 · Last updated May 03, 2026 · Updated 11 times

Summary

This study tests an experimental oral medicine (PF-07328948) in 620 adults with heart failure. Participants will be randomly assigned to receive the drug or a placebo for 36 weeks. The goal is to see if the drug improves walking distance, heart failure symptoms, and quality of life, while monitoring for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

"Multiprofile Hospital for Active Treatment Puls" AD
RECRUITING

Blagoevgrad, 2700, Bulgaria
ACV Clinic
RECRUITING

Greater Sudbury, Ontario, P3E 5M4, Canada
AGEL Stredomoravska nemocnicni, a.s., Nemocnice AGEL Prerov
RECRUITING

Přerov, 751 52, Czechia
Amavita Research Services
RECRUITING

North Miami Beach, Florida, 33169, United States
Ascension Saint Agnes Heart Care
RECRUITING

Baltimore, Maryland, 21229, United States
CEPIC - Centro Paulista de Investigação Clínica
NOT_YET_RECRUITING

São Paulo, 04266-010, Brazil
CHU de Quebec - Université Laval - Hotel Dieu de Quebec
RECRUITING

Québec, Quebec, G1R 2J6, Canada
CHUS - Hospital Clinico Universitario
NOT_YET_RECRUITING

Santiago de Compostela, A Coruña [LA Coruña], 15706, Spain
CIUSSS- saguenay-Lac-Saint-Jean
RECRUITING

Chicoutimi, Quebec, G7H 5H6, Canada
CMed Rehabilitacios es Diagnosztikai Kozpont
NOT_YET_RECRUITING

Székesfehérvár, Fejér, 8000, Hungary
CardioQuest Research Centre
NOT_YET_RECRUITING

Sarnia, Ontario, N7T 4P5, Canada
Cardresearch - Cardiologia Assistencial e Pesquisa
NOT_YET_RECRUITING

Belo Horizonte, Minas Gerais, 30150-274, Brazil
Centre Hospitalier intercommunal de Toulon La Seyne sur Mer
RECRUITING

Toulon, Provence-Alpes-Côte d'Azur Region, 83100, France
Centre intégré de santé et de services sociaux de Lanaudière - Hopital Pierre-Le Gardeur.
RECRUITING

Terrebonne, Quebec, J6V 2H2, Canada
Centro Avançado De Pesquisa, Estudos E Diagnóstico (CAPED) - Centro Médico RibeirãoShopping
NOT_YET_RECRUITING

Ribeirão Preto, São Paulo, 14026-900, Brazil
Chesapeake Cardiac Care
NOT_YET_RECRUITING

Bowie, Maryland, 20715, United States
Chicago Medical Research
RECRUITING

Hazel Crest, Illinois, 60429, United States
Chu Grenoble Alpes
RECRUITING

Grenoble, 38700, France
Clinical Site Partners, LLC dba Flourish Research
RECRUITING

Winter Park, Florida, 32789, United States
Clinique de Médecins Spécialistes
RECRUITING

Shebrooke, Quebec, J1E 0N8, Canada
Community Care Building
RECRUITING

Winchester, Ontario, K0C 2K0, Canada
Comprehensive Cardiovascular Care
RECRUITING

Santa Maria, California, 93454, United States
CoraCentro Pesquisa Clinica
NOT_YET_RECRUITING

Porto Alegre, Rio Grande do Sul, 90840-440, Brazil
Corcare
NOT_YET_RECRUITING

Toronto, Ontario, M1B 5N1, Canada
Da Vinci Magánklinika
RECRUITING

Pécs, Baranya, 7635, Hungary
Diagnostic Consultative Center "Ascendent"
RECRUITING

Sofia, Sofia (stolitsa), 1202, Bulgaria
Diagnostic Consultative Center - 1 Lom EOOD
RECRUITING

Lom, Montana, 3600, Bulgaria
Diagnostic Consultative Center Aleksandrovska
RECRUITING

Sofia, Sofia (stolitsa), 1431, Bulgaria
Diex Recherche Sherbrooke Est
RECRUITING

Sherbrooke, Quebec, J1E 0N8, Canada
Diex Recherche Trois-Rivieres
RECRUITING

Trois-Rivières, Quebec, G9A 4P3, Canada
EDUMED s.r.o.
RECRUITING

Jaroměř, 551 01, Czechia
EFERTUS healthcare s.r.o.
RECRUITING

Brno-Židenice, 615 00, Czechia
Eszak-Pesti Centrumkorhaz-Honvedkorhaz
RECRUITING

Budapest, 1134, Hungary
Ezüstfény Klinika Kft
RECRUITING

Budapest, 1106, Hungary
FOMAT Medical Research
RECRUITING

Santa Maria, California, 93454, United States
FWD Clinical Research
RECRUITING

Boca Raton, Florida, 33486, United States
Fakultni nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 05, Czechia
Flourish Research - Bowie
NOT_YET_RECRUITING

Bowie, Maryland, 20715, United States
Flourish Research Acquisition, LLC dba Flourish Research - North Miami
RECRUITING

Miami, Florida, 33138, United States
Fundação Faculdade Regional de Medicina de São José do Rio Preto
NOT_YET_RECRUITING

São José do Rio Preto, São Paulo, 15090000, Brazil
Guangdong Provincial People's Hospital
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510080, China
Hainan General Hospital
RECRUITING

Haikou, Hainan, 570311, China
Headlands Horizons, LLC dba Headlands Research-Brownsville
RECRUITING

Brownsville, Texas, 78526, United States
Health Sciences North Research Institute
RECRUITING

Greater Sudbury, Ontario, P3E 5J1, Canada
Hospital Clinico de Valencia
RECRUITING

Valencia, Valenciana, Comunitat, 46010, Spain
Hospital General Universitario de Valencia
NOT_YET_RECRUITING

Valencia, 46014, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, Barcelona [barcelona], 08035, Spain
Hospital Universitari de Bellvitge
NOT_YET_RECRUITING

L'Hospitalet de Llobregat, Catalunya [cataluña], 08907, Spain
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, 46026, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, Madrid, Comunidad de, 28046, Spain
Hospital Universitario Puerta de Hierro
RECRUITING

Majadahonda, Madrid, 28220, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, Madrid, Comunidad de, 28034, Spain
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, Catalunya [cataluña], 08041, Spain
Hôpital Arnaud de Villeneuve - CHU Montpellier
NOT_YET_RECRUITING

Montpellier, Hérault, 34090, France
Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes
RECRUITING

Saint-Herblain, Loire-atlantique, 44800, France
Incor - Instituto do Coracao
NOT_YET_RECRUITING

São Paulo, 05403-000, Brazil
Infinite Clinical Research
RECRUITING

Miami, Florida, 33133, United States
Instituto de Pesquisa clinica de Campinas
RECRUITING

Campinas, São Paulo, 13060-080, Brazil
Jacksonville Center for Clinical Research
RECRUITING

Jacksonville, Florida, 32216, United States
Jahn Ferenc Dél-pesti Hospital
RECRUITING

Budapest, 1204, Hungary
Jinan Central Hospital
NOT_YET_RECRUITING

Jinan, Shandong, 250013, China
Kardio Brynow
RECRUITING

Katowice, Silesian Voivodeship, 40-555, Poland
Kardiologicka ambulance Brno s.r.o.
RECRUITING

Brno-Královo Pole, 612 00, Czechia
Kasugai Municipal Hospital
RECRUITING

Kasugai, Aichi-ken, 486-8510, Japan
Kishiwada Tokushukai Hospital
RECRUITING

Kishiwada, Osaka, 596-0042, Japan
Koga General Hospital
RECRUITING

Koga, Ibaraki, 306-0041, Japan
L2IP - Instituto de Pesquisas Clínicas
RECRUITING

Brasília, Federal District, 70.200-730, Brazil
L2IP - Instituto de Pesquisas Clínicas
RECRUITING

Brasília, Federal District, 70200730, Brazil
MHAT - Heart and Brain
ACTIVE_NOT_RECRUITING

Pleven, 5804, Bulgaria
MHAT Hadzhi Dimitar
RECRUITING

Sliven, 8800, Bulgaria
Medical Center Hera - Kyustendil EOOD
RECRUITING

Kyustendil, 2500, Bulgaria
Medical Center Hera EOOD
RECRUITING

Sofia, 1510, Bulgaria
Multiprofile Hospital for Active Treatment "Knyaginya Klementina" - Sofia EAD
RECRUITING

Sofia, Sofia (stolitsa), 1233, Bulgaria
Multiprofile Hospital for Active Treatment Dr. Tota Venkova AD
RECRUITING

Gabrovo, 5300, Bulgaria
NMH Clinical Research Unit
RECRUITING

Chicago, Illinois, 60611, United States
NZOZ Centrum Medyczne KERmed
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-231, Poland
NZOZ Sopockie Centrum Badan Kardiologicznych Pro Cordis Pawel Miekus
RECRUITING

Sopot, Pomeranian Voivodeship, 81-717, Poland
Nagasaki Harbor Medical Center
RECRUITING

Nagasaki, 850-8555, Japan
Nagoya Tokushukai General Hospital
RECRUITING

Kasugai, Aichi-ken, 487-0016, Japan
National Heart Institute
RECRUITING

Beverly Hills, California, 90211, United States
National Hospital Organization Iwakuni Clinical Center
RECRUITING

Iwakuni, Yamaguchi, 740-8510, Japan
National Hospital Organization Mie Chuo Medical Center
RECRUITING

Tsu, Mie-ken, 514-1101, Japan
National Hospital Organization Saitama Hospital
RECRUITING

Wako, Saitama, 351-0102, Japan
National Hospital Organization Sendai Medical Center
RECRUITING

Sendai, Miyagi, 983-8520, Japan
National Hospital Organization Tokyo Medical Center
RECRUITING

Meguro-Ku, Tokyo, 152-8902, Japan
National Hospital Organization Yokohama Medical Center
RECRUITING

Yokohama, Kanagawa, 245-8575, Japan
New Medical Center Kft.
RECRUITING

Sopron, H-9400, Hungary
NewHeart Watanabe Institute
RECRUITING

Suginami, Tokyo, 168-0065, Japan
NexGen Research
RECRUITING

Fort Wayne, Indiana, 46804, United States
NexGen Research
RECRUITING

Lima, Ohio, 45801, United States
Ninewells Hospital and Medical School
RECRUITING

Dundee, Dundee CITY, DD1 9SY, United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation Trust
RECRUITING

Norwich, Norfolk, NR4 7UY, United Kingdom
North Dallas Research Associates
RECRUITING

McKinney, Texas, 75069, United States
Northwest Houston Heart Center
RECRUITING

Tomball, Texas, 77375, United States
Northwestern Memorial HealthCare - Arkes Pavilion
RECRUITING

Chicago, Illinois, 60611, United States
Northwestern Memorial HealthCare - Feinberg Pavilion
RECRUITING

Chicago, Illinois, 60611, United States
Northwestern Memorial HealthCare - Galter Pavilion
RECRUITING

Chicago, Illinois, 60611, United States
Northwestern Memorial Hospital Investigational Drug Service (IDS)
RECRUITING

Chicago, Illinois, 60611, United States
Northwestern University
RECRUITING

Evanston, Illinois, 60208, United States
Núcleo de Pesquisa Clínica do Rio Grande do Sul
NOT_YET_RECRUITING

Porto Alegre, Rio Grande do Sul, 90430-001, Brazil
Orange County Research Center
RECRUITING

Lake Forest, California, 92630, United States
Parc de Salut Mar - Hospital del Mar
RECRUITING

Barcelona, Barcelona [barcelona], 08003, Spain
Peking University First Hospital
RECRUITING

Beijing, Beijing Municipality, 100034, China
QEII Health Sciences Centre - Victoria General Site
RECRUITING

Halifax, Nova Scotia, B3H 3A7, Canada
Reid Physician Associates
RECRUITING

Richmond, Indiana, 47374, United States
Research and Cardiovascular Corp.
NOT_YET_RECRUITING

Ponce, 00717, Puerto Rico
Richmond Clinical Trials
RECRUITING

Richmond, British Columbia, V6V 2L1, Canada
SP ZOZ w Puławach
RECRUITING

Puławy, Lublin Voivodeship, 24-100, Poland
Sagamihara Kyodo Hospital
RECRUITING

Sagamihara, Kanagawa, 252-5188, Japan
Sdružené Zdravotnické Zařízení Krnov
RECRUITING

Krnov, Moravian-Silesian Region, 794 01, Czechia
Seikeikai New Tokyo Heart Clinic
RECRUITING

Matsudo, Chiba, 271-0077, Japan
Sekino Hospital
RECRUITING

Toshimaku, Tokyo, 171-0014, Japan
Semmelweis Egyetem
RECRUITING

Budapest, 1122, Hungary
Shanghai Tongji Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200065, China
Showa General Hospital
RECRUITING

Kodaira-shi, Tokyo, 187-8510, Japan
South Eastern Health and Social Care Trust
RECRUITING

Belfast, BT16 1RH, United Kingdom
St Richard's Hospital
RECRUITING

Chichester, WEST Sussex, PO19 6SE, United Kingdom
St. George's Hospital
RECRUITING

London, England, SW17 0QT, United Kingdom
Teine Keijinkai Hospital
RECRUITING

Sapporo, Hokkaido, 006-8555, Japan
The First Affiliated Hospital of University of South China
RECRUITING

Hengyang, China
The Second Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410011, China
Tianjin People' s Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300121, China
Toho University Sakura Medical Center
RECRUITING

Sakura, Chiba, 285-8741, Japan
Tokyo Metropolitan Toshima Hospital
RECRUITING

Itabashi-ku, Tokyo, 173-0015, Japan
UNESP - Faculdade de Medicina da Universidade Estadual Paulista
RECRUITING

Botucatu, SÃO PAUL, 18618-970, Brazil
University Multiprofile Hospital for Active Treatment "Sveti Georgi" EAD
RECRUITING

Plovdiv, 4002, Bulgaria
University Multiprofile Hospital for Active Treatment Sveta Ekaterina EAD
RECRUITING

Sofia, Sofia (stolitsa), 1431, Bulgaria
VASOMED Clinic s.r.o.
RECRUITING

Ostrava, 710 00, Czechia
Valley Regional Medical Center
RECRUITING

Brownsville, Texas, 78526, United States
Velocity Clinical Research, Lincoln, Pioneer Heart Institute
RECRUITING

Lincoln, Nebraska, 68510, United States
Winchester District Memorial Hospital
RECRUITING

Winchester, Ontario, K0C 2K0, Canada
Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu
RECRUITING

Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland
Wycombe General Hospital
RECRUITING

High Wycombe, HP11 2TT, United Kingdom
Yokohama Municipal Citizen's Hospital
RECRUITING

Yokohama, Kanagawa, 221-0855, Japan
Аcibadem City Clinic University MHAT EOOD - Third Clinical Base
RECRUITING

Sofia, 1415, Bulgaria

Conditions

Explore the condition pages connected to this study.

HEART FAILURE