Heart failure drug trial abandoned over safety fears

NCT ID NCT06142383

Terminated Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study aimed to test if a new injectable drug called XXB750 could help control heart failure. It was compared against a placebo (dummy treatment) and an existing pill. The trial was stopped early because more patients getting the new drug experienced worsening heart failure, raising safety concerns.

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Contacts and locations

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Locations

American Clinical Trials

Acworth, Georgia, 30101, United States
Anderson Medical Research

Ft. Washington, Maryland, 20744, United States
Aultman Hospital

Canton, Ohio, 44710, United States
Cardiology Partners Clinical Research Institute

Wellington, Florida, 33449, United States
Dominion Medical Associates

Richmond, Virginia, 23219, United States
Heart Center Research Llc

Huntsville, Alabama, 35801, United States
Heart Clinic of Hammond

Hammond, Louisiana, 70403, United States
Inpatient Research Clinical LLC

Miami Lakes, Florida, 33014, United States
Nature Coast Clinical Research LLC

Inverness, Florida, 34452, United States
NexGen Research

Lima, Ohio, 45801, United States
Novartis Investigative Site

Blagoevgrad, 270 0, Bulgaria
Novartis Investigative Site

Gabrovo, 5300, Bulgaria
Novartis Investigative Site

Kyustendil, 2500, Bulgaria
Novartis Investigative Site

Pleven, 5800, Bulgaria
Novartis Investigative Site

Plovdiv, 4002, Bulgaria
Novartis Investigative Site

Sofia, 1233, Bulgaria
Novartis Investigative Site

Sofia, 1510, Bulgaria
Novartis Investigative Site

Varna, 9010, Bulgaria
Novartis Investigative Site

Xian, Shanxi, 710061, China
Novartis Investigative Site

Berlin, 13347, Germany
Novartis Investigative Site

Cologne, 51065, Germany
Novartis Investigative Site

Gladbeck, 45968, Germany
Novartis Investigative Site

Kiel, 24105, Germany
Novartis Investigative Site

Ludwigshafen, 67067, Germany
Novartis Investigative Site

Papenburg, 26871, Germany
Novartis Investigative Site

Schwäbisch Hall, 74523, Germany
Novartis Investigative Site

Budapest, Pest County, 1134, Hungary
Novartis Investigative Site

Balatonfüred, 8230, Hungary
Novartis Investigative Site

Belagavi, Karnataka, 590010, India
Novartis Investigative Site

Bikaner, Rajasthan, 334003, India
Novartis Investigative Site

Brescia, BS, 25123, Italy
Novartis Investigative Site

Messina, ME, 98125, Italy
Novartis Investigative Site

Milan, MI, 20138, Italy
Novartis Investigative Site

Pordenone, PN, 33170, Italy
Novartis Investigative Site

Roma, RM, 00133, Italy
Novartis Investigative Site

Roma, RM, 00168, Italy
Novartis Investigative Site

Trieste, TS, 34149, Italy
Novartis Investigative Site

Maebashi, Gunma, 371 8511, Japan
Novartis Investigative Site

Kawasaki, Kanagawa, 216-8511, Japan
Novartis Investigative Site

Sagamihara, Kanagawa, 252-0375, Japan
Novartis Investigative Site

Matsumoto, Nagano, 390-8621, Japan
Novartis Investigative Site

Lisbon, 1449-005, Portugal
Novartis Investigative Site

Vila Nova de Gaia, 4434 502, Portugal
Novartis Investigative Site

Bardejov, Slovakia, 085 01, Slovakia
Novartis Investigative Site

Košice, Slovakia, 040 01, Slovakia
Novartis Investigative Site

Martin, Slovakia, 036 01, Slovakia
Novartis Investigative Site

Nitra, Slovakia, 949 11, Slovakia
Novartis Investigative Site

Prešov, Slovakia, 080 01, Slovakia
Novartis Investigative Site

Svidník, Slovakia, 089 01, Slovakia
Novartis Investigative Site

Santiago Compostela, A Coruna, 15706, Spain
Novartis Investigative Site

Huelva, Andalusia, 21005, Spain
Novartis Investigative Site

Majadahonda, Madrid, 28222, Spain
Novartis Investigative Site

Las Palmas GC, 35010, Spain
Novartis Investigative Site

Madrid, 28041, Spain
Novartis Investigative Site

Málaga, 29010, Spain
Novartis Investigative Site

Valencia, 46010, Spain
Novartis Investigative Site

Valencia, 46026, Spain
Novartis Investigative Site

Taichung, 40447, Taiwan
Revival Research Institute

Troy, Michigan, 48084, United States
SEC Clinical Research

Dothan, Alabama, 36305, United States
Tennessee Center For Clinical Trials

Tullahoma, Tennessee, 37388, United States
The Research Group

Lexington, Kentucky, 40503, United States

Conditions

Explore the condition pages connected to this study.

HEART FAILURE