Heart failure Drug's blood pressure secrets revealed in new study

NCT ID NCT04649229

First seen Dec 10, 2025 · Last updated Jun 11, 2026 · Updated 20 times

Summary

This study looked at how the heart failure medication Entresto (LCZ696) lowers blood pressure and affects sodium excretion. 46 stable heart failure patients participated in a crossover trial where they received either a placebo or a drug called aprepitant alongside Entresto. The goal was to understand the body's response to the medication, not to test a new treatment.

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Contacts and locations

Locations

  • Yale New Haven Hospital

    New Haven, Connecticut, 06520, United States

Conditions

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