Heart drug study aims to speed up treatment for weakened hearts

NCT ID NCT06195930

Summary

This study tested whether people with chronic heart failure could safely start taking the medication vericiguat at a higher dose than usual. Researchers wanted to see if starting at 5 mg instead of 2.5 mg would help patients reach the full 10 mg treatment dose faster, potentially improving their heart function sooner. The 4-week study with 106 participants focused on monitoring side effects like low blood pressure and dizziness to ensure the higher starting dose was well-tolerated alongside their regular heart medications.

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Contacts and locations

Locations

  • ASST Papa Giovanni XXIII

    Bergamo, Lombardy, 24127, Italy

  • ASST Spedali Civili di Brescia

    Brescia, Lombardy, 25123, Italy

  • Advanced Cardiovascular, LLC - Alexander City

    Alexander City, Alabama, 35010, United States

  • Ascension Saint Agnes Heart Care

    Baltimore, Maryland, 21229, United States

  • CEDIC Centro de Investigación Clínica | Buenos Aires, Argentina

    CABA, Ciudad Auton. de Buenos Aires, C1018DES, Argentina

  • Capio Citykliniken - Hjartmottagning

    Lund, 222 21, Sweden

  • Centro de Investigacion y Prevencion Cardiovascular | Sede Recoleta

    Buenos Aires, Ciudad Auton. de Buenos Aires, C1119ACN, Argentina

  • Centro de Investigaciones Clinicas del Litoral | Santa Fe, Argentina

    Santa Fe, S3000FWO, Argentina

  • Centrum Medyczne Zdrowa

    Krakow, 31-216, Poland

  • Chear Center LLC

    New York, New York, 10455, United States

  • Clinical Best Solutions Sp. Z O.O. Sp.K.

    Lublin, 20-011, Poland

  • Clinical Best Solutions Sp. Z O.O. Sp.K.

    Warsaw, 00-710, Poland

  • Complex Rendelo Med Zrt.

    Székesfehérvár, 8000, Hungary

  • Consultorios Integrados Rosario | Instituto Medico de la Fundacion de Estudios Clinicos

    Rosario, Santa Fe Province, S2000DEJ, Argentina

  • Coromed Smo Kft

    Pécs, 7623, Hungary

  • Eszak-Pesti Centrumkorhaz-Honvedkorhaz

    Budapest, 1134, Hungary

  • Fondazione IRCCS Policlinico San Matteo

    Pavia, Lombardy, 27100, Italy

  • Hospital Clinico Universitario de Santiago de Compostela | Cardiology Department

    Santiago de Compostela, A Coruña, 15706, Spain

  • Hospital Clínico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Ramon y Cajal | Cardiology - Research Unit

    Madrid, 28034, Spain

  • Hospital Universitari de Bellvitge | Bellvitge Biomedical Research Institute - Cardiology Department

    Barcelona, 08907, Spain

  • Hospital del Mar | Cardiology Department

    Barcelona, 08003, Spain

  • Hospital la Paz

    Madrid, 28046, Spain

  • IRCCS Centro Cardiologico Monzino

    Milan, Lombardy, 20138, Italy

  • IRMED Osrodek Badan Klinicznych

    Piotrkow Trybunalski, 97-300, Poland

  • Instituto de Cardiologia de Corrientes Juana F. Cabral | Corrientes, Argentina

    Corrientes, 3400, Argentina

  • Karolinska Universitetssjukhuset

    Stockholm, 17176, Sweden

  • Malopolskie Centrum Sercowo-Naczyniowe PAKS

    Chrzanów, 32-500, Poland

  • NZOZ "Twoja Przychodnia" Sp. z o.o.

    Lublin, 20-857, Poland

  • Reid Physician Associates | Cardiology Department

    Richmond, Indiana, 47374, United States

  • Semmelweis Egyetem Belgyógyaszati és Haematológiai Klinika, Kardiológia

    Budapest, 1088, Hungary

  • Somogy Varmegyei Kaposi Mor Oktato Korhaz

    Kaposvár, 7400, Hungary

  • St. Louis Heart & Vascular, PC

    St Louis, Missouri, 63136, United States

  • Tolna Varmegyei Balassa Janos Korhaz

    Szekszárd, 7100, Hungary

  • Vita Longa Sp. z o.o.

    Katowice, 40-748, Poland

Conditions

Explore the condition pages connected to this study.