Heart implant could replace daily blood thinners for millions

NCT ID NCT03795298

Completed Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

Summary

This study tested whether a small device implanted in the heart is a good alternative to taking daily blood thinners for people who have had a procedure to treat atrial fibrillation (AFib). It involved 1,600 high-risk patients who were randomly assigned to receive either the implant or continue with blood-thinning medication. The goal was to see which approach better prevents strokes and serious bleeding.

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Contacts and locations

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Locations

Aarhus University Hospital

Aarhus, 8200, Denmark
Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Advara HeartCare

Brisbane, Queensland, 4120 QLD, Australia
AdventHealth Ocala

Ocala, Florida, 34471, United States
Alaska Regional Hospital

Anchorage, Alaska, 99508, United States
Allgemeines Krankenhaus Altona

Hamburg, 22763, Germany
Arizona Arrhythmia Research Center

Phoenix, Arizona, 85016, United States
Asklepios Klinik Saint Georg

Hamburg, 20099, Germany
Azienda Ospedaliero-Universitaria Citta della Salute e della Scienza di Torino

Torino, 10123, Italy
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
Broward General Medical Center

Fort Lauderdale, Florida, 33316, United States
CHI Franciscan Health System

Tacoma, Washington, 98405, United States
CHRU de Clermont-Ferrand

Clermont-Ferrand, 63000, France
CHRU de Lille

Lille, Hauts-de-France, 59037, France
CHU Grenoble - Hopital Michallon

Grenoble, 38043, France
CHU Henri Mondor

Créteil, Île-de-France Region, 94010, France
Cardioangiologisches Centrum Bethanien

Frankfurt, 60431, Germany
Cardiology Clinic of San Antonio

San Antonio, Texas, 78229, United States
Cardiovascular Associates of the Delaware Valley

Haddon Heights, New Jersey, 08035, United States
Carolinas Medical Center

Charlotte, North Carolina, 28203, United States
Catholic Medical Center

Manchester, New Hampshire, 03102, United States
Centennial Medical Center

Nashville, Tennessee, 37203, United States
Centre Hôpital Universitaire Rangueil

Toulouse, 31400, France
Centro Cardiologico Monzino

Milan, 20138, Italy
Centura Health

Littleton, Colorado, 80120, United States
Chippenham Medical Center

Richmond, Virginia, 23225, United States
Christus Trinity Mother Frances Health System

Tyler, Texas, 75702, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Clinico de Valladolid

Valladolid, 47005, Spain
Clinique Pasteur

Toulouse, 31076, France
DHZC - Deutsches Herzzentrum der Charité

Berlin, 12203, Germany
Duke University Medical Center

Durham, North Carolina, 27705, United States
Edward Hospital

Naperville, Illinois, 60540, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Grandview Medical Center

Birmingham, Alabama, 35243, United States
HealthEast St. Joseph's Hospital

Saint Paul, Minnesota, 55102, United States
Heart Center Research

Huntsville, Alabama, 35801, United States
Heart Clinic Arkansas

Little Rock, Arkansas, 72205, United States
HeartPlace Mid-Cities EP

Bedford, Texas, 76021, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Hospital Alvaro Cunqueiro

Vigo, 36312, Spain
Hospital Clinico Salamanca

Salamanca, 37007, Spain
Hospital Clinico San Carlos

Madrid, 28040, Spain
Hospital Europeen Georges-Pompidou

Paris, 75015, France
Hospital General Universitario

Alicante, 3010, Spain
Hospital Puerta Del Mar

Cadiz, 11009, Spain
Hospital de la Pitie-Salpetriere

Paris, Île-de-France Region, 75013, France
Intermountain Medical Center

Murray, Utah, 84107, United States
Iowa Heart Center

Des Moines, Iowa, 50266, United States
Kaiser Permanente Santa Clara Medical Center

Santa Clara, California, 95051, United States
Kansas City Cardiac Arrhythmia Research

Overland Park, Kansas, 66215, United States
Klinik für Kardiologie, Angiologie und Intensivmedizin Mittelallee

Berlin, 13353, Germany
Klinikum Coburg GmbH

Coburg, 96450, Germany
Klinikum St. Georg

Leipzig, 4129, Germany
Lahey Clinic Hospital

Burlington, Massachusetts, 01805, United States
Lankenau Institute for Medical Research

Wynnewood, Pennsylvania, 19096, United States
Lindner Center for Research and Education at Christ Hospital

Cincinnati, Ohio, 45219, United States
Manatee Memorial Hospital

Bradenton, Florida, 34205, United States
Marian Regional Medical Center

Santa Maria, California, 93454, United States
Marin General Hospital

Larkspur, California, 94939, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Medical Center of the Rockies (Loveland)

Loveland, Colorado, 80538, United States
Memorial Hospital

Colorado Springs, Colorado, 80909, United States
Mercy Research

St Louis, Missouri, 63141, United States
Methodist Hospital of Indianapolis

Indianapolis, Indiana, 46202, United States
Mills Peninsula Health Services

Burlingame, California, 94010, United States
Monash Health

Clayton, Victoria, 3168, Australia
Monongalia General Hospital

Morgantown, West Virginia, 26506, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Mount Sinai Medical Center

New York, New York, 10029, United States
MyMichigan Medical Center Midland

Midland, Michigan, 48670, United States
Nebraska Heart Institute

Lincoln, Nebraska, 68526, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
New York University Medical Center

New York, New York, 10016, United States
Northwell Health

Bay Shore, New York, 11706, United States
OhioHealth Research and Innovation Institute - Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Onze Lieve Vrouw Ziekenhuis

Aalst, East Flanders, 9300, Belgium
Overland Park Regional Medical Center

Kansas City, Kansas, 66160, United States
PeaceHealth Southwest Medical

Vancouver, Washington, 98664, United States
Phoenix Cardiovascular Research Group

Phoenix, Arizona, 85016, United States
Pinnacle Health at Harrisburg Hospital

Harrisburg, Pennsylvania, 17101, United States
Poznan University of Medical Sciences

Poznan, 61-848, Poland
Presbyterian University of Pennsylvania Medical Center

Philadelphia, Pennsylvania, 19104, United States
Rex Hospital

Raleigh, North Carolina, 27607, United States
Saint Thomas Health

Nashville, Tennessee, 37205, United States
Scripps Memorial Hospital

La Jolla, California, 92037, United States
Sharp Memorial Hospital

San Diego, California, 92123, United States
St. Alphonsus Regional Medical Center

Boise, Idaho, 83704, United States
St. Antonius Ziekenhuis

Nieuwegein, Utrecht, 3430 EM, Netherlands
St. Bernard's Medical Center

Jonesboro, Arkansas, 72401, United States
St. John's Hospital

Springfield, Illinois, 62701, United States
St. Josefs-Hospital GmbH

Wiesbaden, 65189, Germany
St. Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
St. Lukes Idaho Cardiology Associates

Boise, Idaho, 83712, United States
St. Mark's Hospital

Salt Lake City, Utah, 84124, United States
St. Vincent Heart Center of Indiana

Indianapolis, Indiana, 46290, United States
St. Vincent's Medical Center

Jacksonville, Florida, 32204, United States
St.Johann Nepomuk Katholisches Hospitalvereinigung Thüringen GmbH

Erfurt, 99097, Germany
Tallahassee Memorial Hospital

Tallahassee, Florida, 32308, United States
Texas Cardiac Arrhythmia Research

Austin, Texas, 78705, United States
The Heart Hospital Baylor Plano

Plano, Texas, 75093, United States
Universitaetsklinikum Schleswig-Holstein

Lübeck, D-23538, Germany
Universitatsklinik Greifswald

Greifswald, 17475, Germany
University of Kansas Hospital

Kansas City, Kansas, 66160, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15237, United States
University of Southern California Hospital

Los Angeles, California, 90017, United States
Valley Hospital

Ridgewood, New Jersey, 07450, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Wellstar Kennestone Hospital

Marietta, Georgia, 30060, United States
West Virginia University Hospitals

Morgantown, West Virginia, 26506, United States
Yale University School of Medicine

New Haven, Connecticut, 06510, United States
York Hospital

York, Pennsylvania, 17403, United States

Conditions

Explore the condition pages connected to this study.

ATRIAL FIBRILLATION