New imaging method could save lives in heart attack patients with multiple blockages

NCT ID NCT05818475

First seen May 01, 2026 · Last updated May 07, 2026 · Updated 1 time

Summary

This study compares two imaging methods to guide treatment of non-emergency blockages in heart attack patients who have multiple blocked arteries. About 1,800 participants will be randomly assigned to either a new angiography-derived blood flow measurement or standard angiography. The goal is to see which approach better prevents death, another heart attack, stroke, or the need for repeat procedures, while also reducing kidney injury and bleeding risks.

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Contacts and locations

Locations

  • AORN Sant'Anna e San Sebastiano

    Caserta, Italy

  • ASST Papa Giovanni XXIII

    Bergamo, Italy

  • AUSL Bologna Ospedale Maggiore

    Bologna, BO, 40133, Italy

  • AUSL Piacenza

    Piacenza, PC, Italy

  • AUSL Romagna Ospedale degli Infermi Rimini

    Rimini, RN, Italy

  • AUSL Romagna Santa Maria delle Croci Ravenna

    Ravenna, Italy

  • Arcispedale Santa Maria Nuova di Reggio Emilia

    Reggio Emilia, RE, 42123, Italy

  • Azienda Ospedaliero Universitaria Integrata di Verona

    Verona, VR, Italy

  • Azienda Ospedaliero Universitaria Mater Domini

    Catanzaro, Italy, Italy

  • Azienda Ospedaliero Universitaria Pisana

    Pisa, Italy

  • Azienda Ospedaliero Universitaria di Ferrara

    Ferrara, FE, 44124, Italy

  • Azienda Ospedaliero Universitaria di Parma

    Parma, PR, Italy

  • NICVD Karachi

    Karachi, Pakistan

  • Ospedale Annunziata

    Cosenza, Italy, 87100, Italy

  • Ospedale Civile di Baggiovara

    Baggiovara, MO, Italy

  • Ospedale Maggiore della Carità Novara

    Novara, Italy

  • Ospedale Mater Salutis Legnago

    Legnago, VR, Italy

  • Ospedale Santa Maria Goretti

    Latina, Italy

  • Ospedale Santa Maria della Misericordia Rovigo

    Rovigo, RO, Italy

  • Ospedale dell'Angelo Mestre

    Mestre, VE, 30100, Italy

  • Ospedale di Bolzano

    Bolzano, Italy, 39100, Italy

  • Policlinico Casilino

    Roma, Italy

Conditions

Explore the condition pages connected to this study.