Healthy volunteers help unravel metabolism of liver disease drug candidate
NCT ID NCT03159390
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 24 times
Summary
This study looked at how healthy adults process a compound called ornithine phenylacetate (OP), which is being explored as a treatment for liver disease. Twenty volunteers aged 40-70 received OP by mouth and stable tracers by IV, with blood, urine, and muscle samples collected. The goal was to understand how OP is broken down into amino acids like glutamate and glutamine, not to test a treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Texas A&M University-CTRAL
College Station, Texas, 77843-4253, United States
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