New drug combos tested in battle against advanced head & neck cancer
NCT ID NCT05909904
Summary
This study is testing whether an immunotherapy drug called tislelizumab, either alone or combined with other experimental drugs, can help control advanced head and neck cancer that has returned or spread. About 160 patients who have not yet received treatment for their advanced cancer will be randomly assigned to different treatment groups to see which approach works best. The main goals are to see if the treatments shrink tumors and to monitor side effects.
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Contacts and locations
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Locations
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Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital
Hefei, Anhui, 230088, China
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Arensia Exploratory Medicine Llc
Tbilisi, 0112, Georgia
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Asan Medical Center
Seoul, Seoul Teugbyeolsi, 05505, South Korea
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Beijing Cancer Hospital
Beijing, Beijing Municipality, 100142, China
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Beijing Tongren Hospital, Cmu
Beijing, Beijing Municipality, 100010, China
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British Columbia Cancer Agency the Vancouver Centre
Vancouver, British Columbia, V5Z 4E6, Canada
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Cancer Care Northwest
Spokane Valley, Washington, 99216, United States
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Cancer Research South Australia
Adelaide, South Australia, 5000, Australia
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Centre Antoine Lacassagne
Nice, 06100, France
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Changhua Christian Hospital
Changhua, 50006, Taiwan
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China Medical University Hospital
Taichung, 40447, Taiwan
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Florida Cancer Specialist Research Institute Lake Nona
Orlando, Florida, 32827, United States
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Florida Cancer Specialist Research Institute Panhandle
Tallahassee, Florida, 32308, United States
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Fondazione Irccs Istituto Nazionale Dei Tumori
Milan, 20133, Italy
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Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
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Gold Coast Private Hospital
Gold Coast, Queensland, 4215, Australia
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Greenslopes Private Hospital
Greenslopes, Queensland, 4120, Australia
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Hospital Clinico San Carlos
Madrid, 28040, Spain
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Hospital Universitario Miguel Servet
Zaragoza, 50009, Spain
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Hospital Universitario Virgen Del Rocio
Seville, 41013, Spain
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Hunan Cancer Hospital
Changsha, Hunan, 410013, China
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Ico Lhospitalet Hospital Duran I Reynals
Barcelona, 08908, Spain
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Ico Site Rene Gauducheau
SaintHerblain, 44805, France
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Institut Curie Paris
Paris, 75005, France
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Institut Gustave Roussy
Villejuif, 94805, France
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Istituto Clinico Humanitas
Rozzano, 20089, Italy
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Istituto Europeo Di Oncologia
Milan, 20141, Italy
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Keimyung University Dongsan Hospital
Dalseogu, Daegu Gwang'yeogsi, 42601, South Korea
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Medical Park Izmir Hospital
Izmir, 35575, Turkey (Türkiye)
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National Cancer Center
Goyang-si, Gyeonggi-do, 10408, South Korea
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National Cancer Centre Singapore
Singapore, 168583, Singapore
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National Cheng Kung University Hospital
Tainan, 704, Taiwan
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Nepean Hospital
Kingswood, New South Wales, 2747, Australia
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North Shore Private Hospital
St Leonards, New South Wales, 2065, Australia
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Northeast Health Wangaratta
Wangaratta, Victoria, 3677, Australia
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Northwest Cancer Specialist, Pc(Us Oncology Research)
Vancouver, Washington, 98684, United States
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Oncology and Hematology Associates of Southwest Virginia, Inc (Us Oncology Research)
Blacksburg, Virginia, 24060, United States
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Ramathibodi Hospital Mahidol University
Bangkok, 10400, Thailand
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Rocky Mountain Cancer Centers, Llp(Us Oncology Research)
Lone Tree, Colorado, 80124, United States
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Royal Marsden Hospital
London, SW3 6JJ, United Kingdom
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Royal Marsden Hospital Sutton
Sutton, SM2 5PT, United Kingdom
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Samsung Medical Center
Seoul, Seoul Teugbyeolsi, 06351, South Korea
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Scientific Institute of Pavia Maugeri
Pavia, 27100, Italy
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital
Seoul, Seoul Teugbyeolsi, 03080, South Korea
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Severance Hospital Yonsei University Health System
Seoul, Seoul Teugbyeolsi, 03722, South Korea
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Shandong Cancer Hospital
Jinan, Shandong, 250117, China
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Shanghai East Hospital
Shanghai, Shanghai Municipality, 200120, China
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Sichuan Cancer Hospital and Institute
Chengdu, Sichuan, 610041, China
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Siriraj Hospital
Bangkok, 10700, Thailand
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Songklanagarind Hospital (Prince of Songkhla University)
Hat Yai, 90110, Thailand
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Srinagarind Hospital (Khon Kaen University)
Muang, 40002, Thailand
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St John of God, Murdoch
Murdoch, Western Australia, 6150, Australia
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Stanford Medicine
Stanford, California, 94305, United States
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Sun Yat Sen University Cancer Center
Guangzhou, Guangdong, 510060, China
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 630014, China
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The First Affiliated Hospital of Nanchang University Branch Donghu
Nanchang, Jiangxi, 330006, China
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The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, 215006, China
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The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, 361003, China
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The First Hospital of Jilin University
Changchun, Jilin, 130021, China
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The Ottawa Hospital Cancer Centre
Ottawa, Ontario, K1H 8L6, Canada
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The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310009, China
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The Second Xiangya Hospital of Central South University
Changsha, Hunan, 410011, China
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The Tumor Hospital Affiliated to Guangxi Medical University
Nanning, Guangxi, 530021, China
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Tianjin Medical University Cancer Institute & Hospital
Tianjin, Tianjin Municipality, 300060, China
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Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
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Tr Trakya University Health Research and Application Center (Hospital)
Edirne, 22030, Turkey (Türkiye)
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University of Kentucky Markey Cancer Center
Lexington, Kentucky, 40536, United States
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Valkyrie Clinical Trials
Los Angeles, California, 90067, United States
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West China Hospital, Sichuan University
Chengdu, Sichuan, 610041, China
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Xiangya Hospital of Central South University
Changsha, Hunan, 410008, China
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Zhejiang Cancer Hospital
Hangzhou, Zhejiang, 310022, China
Conditions
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