Radiation blast boosts cancer drug power in major trial

NCT ID NCT05815927

Recruiting now Disease control Sponsor: European Organisation for Research and Treatment of Cancer - EORTC Source: ClinicalTrials.gov ↗

Summary

This study is testing if adding a precise, high-dose radiation treatment (SABR) to the standard immunotherapy drug pembrolizumab works better than the drug alone for controlling advanced head and neck cancer that has spread to a few other body sites. It will enroll 200 adults whose cancer has 1 to 5 spread-away tumors to see if the combination helps keep the cancer from growing longer and helps people live longer. The main goal is to see if the combined approach improves 'progression-free survival'—the time patients live without their cancer getting worse.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AUSL - Ospedale Infermi
NOT_YET_RECRUITING

Faenza, 48018, Italy
AUSL -Ospedale Umberto I
NOT_YET_RECRUITING

Lugo, 48022, Italy
AUSL Romagna - AUSL Della Romagna -Ospedale Santa Maria delle Croci
NOT_YET_RECRUITING

Ravenna, 48121, Italy
AZ Groeninge Kortrijk - Campus Kennedylaan
RECRUITING

Kortrijk, 8500, Belgium
Azienda Sanitaria Locale Napoli 1 Centro
NOT_YET_RECRUITING

Naples, 80147, Italy
Azienda ospedaliero Univ Policlinico Umberto I
NOT_YET_RECRUITING

Rome, 00161, Italy
CHU-UCL Namur - CHU Site Sainte-Elisabeth-UCL Namur
RECRUITING

Namur, 5000, Belgium
Cliniques Universitaires Saint-Luc
RECRUITING

Brussels, 1200, Belgium
Hospital Universitari Vall d'Hebron -Vall d'Hebron Institut Oncologia
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Universitario San Carlos
RECRUITING

Madrid, 28040, Spain
Hospital Universitario de Gran Canaria Doctor Negrin
RECRUITING

Las Palmas de Gran Canaria, 35010, Spain
ICO L'Hospitalet - Hospital Duran i Reynals (Institut Catala D'Oncologia)
RECRUITING

Barcelona, 08908, Spain
IRCCS - Fondazione Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy
IRCCS--Ospedale Bellaria-Bologna
NOT_YET_RECRUITING

Bologna, 40139, Italy
Inselspital - Inselspital
NOT_YET_RECRUITING

Bern, 3010, Switzerland
Istituto Clinico Humanitas
NOT_YET_RECRUITING

Milan, 20089, Italy
Kantonsspital Aarau
NOT_YET_RECRUITING

Aarau, 5001, Switzerland
Kantonsspital Graubuenden
NOT_YET_RECRUITING

Chur, 7000, Switzerland
Kantonsspital Winterthur
NOT_YET_RECRUITING

Winterthur, 8401, Switzerland
Luzerner Kantonsspital
NOT_YET_RECRUITING

Lucerne, 6004, Switzerland
Oncology Institute of Southern Switzerland (IOSI) - Oncology Institute of Southern Switzerland - Ospedale San Giovanni
NOT_YET_RECRUITING

Bellinzona, 6500, Switzerland
Univ. of Florence -Azienda Ospedaliero-Universitaria Careggi
NOT_YET_RECRUITING

Florence, 50134, Italy
UniversitaetsSpital Zurich
NOT_YET_RECRUITING

Zurich, 8901, Switzerland
VITAZ St Niklaas - VITAZ- Oncology
NOT_YET_RECRUITING

Sint-Niklaas, 9100, Belgium
Ziekenhuis aan de Stroom (ZAS) - ZAS Augustinus (previous GZA)
RECRUITING

Wilrijk, 2610, Belgium

Conditions

Explore the condition pages connected to this study.

OLIGOMETASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK