New hope for liver cancer patients with cirrhosis: safety trial launches
NCT ID NCT06096779
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 3 times
Summary
This study is for people with advanced liver cancer (hepatocellular carcinoma) who also have moderate cirrhosis (Child-Pugh B7 or B8). It tests the safety of two drugs, atezolizumab and bevacizumab, given together or alone as a first treatment. The goal is to see if these drugs are safe enough to use in this specific group of patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Bon Secours St. Mary's Hospital
Richmond, Virginia, 23226-1925, United States
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California Liver Research Institute
Pasadena, California, 91105-2561, United States
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Cedars Sinai Comprehensive Transplant Center
West Hollywood, California, 90048-2422, United States
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Dayton VA Medical Center - NAVREF - PPDS
Dayton, Ohio, 45428-9000, United States
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George Washington University- Medical Faculty Associates
Washington D.C., District of Columbia, 20037, United States
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Harbor UCLA Medical Center
Torrance, California, 90502-2006, United States
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Hartford Healthcare Cancer Institute at Hartford Hospital
Hartford, Connecticut, 06106, United States
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Inova Schar Cancer Institute
Falls Church, Virginia, 22042, United States
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Intermountain Cancer Center
St. George, Utah, 84790, United States
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Intermountain Healthcare
Murray, Utah, 84107-5741, United States
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James J Peters Veterans Administration Medical Center - NAVREF
The Bronx, New York, 10468-3904, United States
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Jefferson Health Honickman Center
Philadelphia, Pennsylvania, 19107, United States
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Kaiser Permanente Westside Medical Center
Hillsboro, Oregon, 97124-5806, United States
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Kelsey Research Foundation
Houston, Texas, 77025-1669, United States
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LSU Health Baton Rouge
Baton Rouge, Louisiana, 70805, United States
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Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Liver Institute at Methodist Dallas
Dallas, Texas, 75203-1260, United States
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Michael E Debakey VA Medical Center - NAVREF - PPDS
Houston, Texas, 77030-4211, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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Moody Outpatient Center ? Parkland Health
Dallas, Texas, 75235, United States
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MorristownMedicalCenter
Morristown, New Jersey, 07962, United States
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NYU Langone Hospital - Long Island
Mineola, New York, 11501-4064, United States
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NYU Langone Medical Center
New York, New York, 10016-9451, United States
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Nashville General Hospital at Meharry
Nashville, Tennessee, 37208-2918, United States
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Northwestern University
Chicago, Illinois, 60611-2908, United States
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OHSU Knight Cancer Institute Hematology Oncology
Portland, Oregon, 97239-3011, United States
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Orlando Health Inc.
Orlando, Florida, 32806, United States
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Our Lady of the Lake Cancer Institute
Baton Rouge, Louisiana, 70808-4300, United States
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Pan American Center for Oncology Trials, LLC
Rio Piedras, 00935, Puerto Rico
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Rocky Mountain Cancer Centers (Williams) - USOR
Denver, Colorado, 80218-1237, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901, United States
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Rutgers Cancer Institute of New Jersey at University Hospital
Newark, New Jersey, 07103, United States
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Saint Luke?s Hospital of Kansas City
Kansas City, Missouri, 64111, United States
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Stanford Health Care
Stanford, California, 94305, United States
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Texas Oncology (Worth) - USOR
Dallas, Texas, 75246-2008, United States
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Texas Oncology - Denison Cancer Center
Denison, Texas, 75020-0084, United States
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The Duchossois Center for Advanced Medicine
Chicago, Illinois, 60637-1426, United States
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The University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104-5020, United States
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The West Clinic (East Campus)
Germantown, Tennessee, 38138-1762, United States
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Tufts Medical Center
Boston, Massachusetts, 02111, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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University of Arizona Cancer Center
Tucson, Arizona, 85724, United States
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University of California Davis Medical Center
Sacramento, California, 95817, United States
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University of California Irvine Medical Center
Orange, California, 92868, United States
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University of Illinois Health Outpatient Care Center
Chicago, Illinois, 60612-4795, United States
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University of Kentucky - Markey Cancer Center
Lexington, Kentucky, 40536-7001, United States
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University of Southern California
Newport Beach, California, 92663, United States
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University of Southern California-Keck School of Medicine -1975 Zonal Ave
Los Angeles, California, 90089-5601, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390-0001, United States
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VCU Medical Center North Hospital
Richmond, Virginia, 23298-5028, United States
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Veterans Affairs Ann Arbor Healthcare System
Ann Arbor, Michigan, 48105, United States
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Veterans Affairs Pittsburgh Healthcare System - NAVREF - PPDS
Pittsburgh, Pennsylvania, 15240, United States
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Virginia Mason Medical Center
Seattle, Washington, 98101, United States
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Washington DC VA Medical Center
Washington D.C., District of Columbia, 20422-0001, United States
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