Could carbon monoxide help Parkinson's? small trial begins

NCT ID NCT07005180

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2a trial tests an oral liquid containing low-dose carbon monoxide (HBI-002) in 36 people with Parkinson's disease. Participants take it daily for 14 days to see if it is safe and tolerable. The study is randomized and placebo-controlled, meaning some get the drug and some get a dummy liquid. It is too early to know if it helps symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
low-dose carbon monoxide liquid (HBI-002)
What this could lead to
If it works, this could point toward a new way to ease symptoms or slow Parkinson's disease progression.
What could go wrong
This is a very early, small phase 2a trial focused on safety, not effectiveness. Carbon monoxide is toxic at high doses, so even low doses carry unknown risks. Results may not lead to a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Quest Research Institute

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

    Contact Email: •••••@•••••

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