Can a simple injection make hysteroscopy Pain-Free?

NCT ID NCT07178379

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether injecting a local anesthetic (mepivacaine) into the ligaments around the cervix can reduce pain during an outpatient hysteroscopy. About 70 women who have never had a hysteroscopy will be randomly assigned to receive either the anesthetic or a placebo. The main goal is to see if the anesthetic lowers pain scores on a standard scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mepivacaine (local anesthetic)
What this could lead to
If it works, this could provide a simple, effective way to reduce pain during hysteroscopy, making the procedure more comfortable for many women.
What could go wrong
This is a small, early-stage trial. The placebo group receives a saline irrigation, not an injection, so blinding is imperfect. The results may not apply to all types of hysteroscopy.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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