New filler aims to restore youthful cheek volume

NCT ID NCT05818709

Completed Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new dermal filler called HAC 22L for improving midface volume loss in adults. About 61 participants received either the filler or delayed treatment. The goal was to see if the filler safely improves cheek fullness. Results are based on doctor ratings and patient satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: HAC 22L (hyaluronic acid dermal filler)
What this could lead to: If it works, this could offer a safe and effective option for restoring midface volume lost with aging.
What could go wrong: This is a small, completed Phase 3 trial with only 61 participants. Results may not apply to everyone, and side effects like swelling or bruising are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FACIAL VOLUME DEFICIT

Contacts and locations

Locations

Antiaging Group Barcelona (AGB) /ID# 245446

Barcelona, 08021, Spain
Dermatologie Mahlow /ID# 243805

Blankenfelde-Mahlow, Brandenburg, 15831, Germany
Grupo Pedro Jaen /ID# 243347

Madrid, 28006, Spain
Haut- und Lasercentrum Potsdam /ID# 243822

Potsdam, Brandenburg, 14467, Germany
Hautarztpraxis Dr. Niesmann und Dr. Othlinghaus /ID# 243802

Bochum, North Rhine-Westphalia, 44793, Germany
Hautok and Hautok-cosmetics /ID# 243800

Munich, Bavaria, 80333, Germany
Hautzentrum Koeln /ID# 244607

Cologne, North Rhine-Westphalia, 50996, Germany
Instituto Medico Miramar /ID# 251640

Málaga, Malaga, 29016, Spain
Instituto de Dermatologia Integral (IDEI) /ID# 245764

Madrid, 28009, Spain
Instituto de Medicina y Dermatologia Avanzada (IMDA) /ID# 243339

Madrid, 28001, Spain
MediCorium Zentrum fuer Dermatologie und Aesthetik /ID# 243799

Oberursel, Hesse, 61440, Germany
Noahklinik GmbH /ID# 244610

Kassel, 34117, Germany
Privatpraxis Dr. Hilton & Partner /ID# 243798

Düsseldorf, North Rhine-Westphalia, 40212, Germany
Privatpraxis fuer Dermatologie und Aesthetik /ID# 243803

München, 80539, Germany
Rosenpark Research /ID# 243804

Darmstadt, Hesse, 64283, Germany
Sclinic /Id# 243340

Madrid, 28001, Spain
Universitaet Hamburg /ID# 251970

Hamburg, 20146, Germany