Could a hyaluronic acid pill protect muscle in alcoholic hepatitis?
NCT ID NCT05018481
First seen Nov 17, 2025 · Last updated Jun 21, 2026 · Updated 29 times
Summary
This early-phase trial is testing whether a form of hyaluronic acid called HA35 can help prevent muscle loss in people with alcoholic hepatitis. 54 participants will take either HA35 or a placebo capsule daily for 90 days. The study involves two in-person visits with muscle biopsies and other tests, plus phone check-ins.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sodium hyaluronate (HA35)
What this could lead to
If it works, this could point toward a way to prevent muscle loss in people with alcoholic hepatitis.
What could go wrong
This is a very early, small trial with only 54 participants. It is testing a mechanism, not a proven treatment, and may not lead to any clinical benefit.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.