New acid reducer shows promise in fighting stomach bug

NCT ID NCT07606833

First seen Jun 01, 2026 · Last updated Jun 23, 2026 · Updated 7 times

Summary

This Phase 3 trial tests whether a new acid-reducing drug, anaprazole, works better than the standard drug esomeprazole when used with bismuth and two antibiotics to treat H. pylori infection. About 556 adults in China will take either anaprazole or esomeprazole pills twice daily for 14 days. The main goal is to see if the infection is gone after treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HELICOBACTER PYLORI INFECTIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shenzhen Hospital of Southern Medical University

    Shenzhen, Guangdong, 518100, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anaprazole sodium (a drug that reduces stomach acid) combined with bismuth, amoxicillin, and clarithromycin

What this could lead to

If successful, this could provide a new treatment option for H. pylori infection, potentially improving eradication rates.

What could go wrong

This is a Phase 3 trial, but results may not apply to all populations. The treatment includes antibiotics, which can cause side effects like diarrhea or allergic reactions.

Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.