Could a simpler pill combo beat the standard cocktail for stomach bug?

NCT ID NCT06412588

First seen Feb 28, 2026 · Last updated May 12, 2026 · Updated 11 times

Summary

This study tested whether a two-drug regimen (vonoprazan plus either amoxicillin or doxycycline) works as well as the standard four-drug therapy for eradicating H. pylori, a bacteria that can cause stomach ulcers. About 579 adults with H. pylori infection took one of three 14-day treatments. The goal was to see which approach is safest, most effective, and easiest for patients to complete.

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Contacts and locations

Locations

  • NanJing Frist Hospital

    Nanjing, Jiangsu, 210006, China

Conditions

Explore the condition pages connected to this study.