Shock therapy for BPH: new electrical ablation may spare sex life

NCT ID NCT07572097

Not yet recruiting Disease control Sponsor: Shanghai East Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new procedure called H-FIRE for men with an enlarged prostate (BPH). Instead of using heat like standard surgeries, H-FIRE uses short electrical pulses to destroy blocking tissue while sparing nerves and muscles. The trial will enroll 288 men aged 50 and older, randomly assigning them to H-FIRE or standard surgery. The goal is to see if H-FIRE can relieve urinary symptoms just as well while better preserving sexual function and bladder control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-Frequency Irreversible Electroporation (H-FIRE) procedure
What this could lead to: If successful, H-FIRE could offer men with enlarged prostate a surgery that relieves urinary symptoms without causing sexual side effects like loss of ejaculation.
What could go wrong: This is an early-stage study with no prior large-scale results. The procedure may not be as effective as standard surgery, and electrical ablation carries risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BPH

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